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Manal Mohamed Anwar Hassan Anwar

Country of origin: Egypt Currently in: Egypt, Cairo General field of specialization: Chemical Sciences
Academic Background


2016 Doctorate Chemical Sciences
Research and Profession

Current Research Activities

Chemical Sciences

pharmaceutical chemistry researches

Publications resulting from Research: 

1. Somaia S. Abd El-Karim, Manal M. Anwar, Neama A. Mohamed, Tamer Nasr, Samia A. Elseginy. Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents. Bioorganic Chemistry (2015) 63: 1–12.

2. Mohsen M. Kamel, Wafaa A. Zaghary, Reem I. Al-Wabli, Manal M. Anwar. Synthetic approaches and potential bioactivity of different functionalized quinazoline and quinazolinone scaffolds. Egypt Pharmaceut J (2016) 15:98–131.

3. Kamelia M. Amin, Yasmin M. Syam, Manal M. Anwar, Hamed I. Ali, Tamer M. Abdel- Ghani, Aya M. Serry. Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells. Bioorganic and Medicinal Chemistry (2017) 25:2423–2436.

4. Mona O. Sarhan, Mohamed A. Motaleb, Ismail T. Ibrahim, Wafaa. A. Zaghary, Manal M. Anwar. Development, Potential Anticancer Activity and the Receptor Profile of Different Functionalized 1,3,5-Triazine Derivatives. Mini-Reviews in Medicinal Chemistry (2018), 18, DOI: 10.2174/1389557517666170927160256.

5. Aisha A.K. Al-Ashmawy, Fatma A. Ragab, Khaled M. Elokely, Manal M. Anwar , Oscar Perez-Leal, Mario C. Rico, John Gordon, Eugeney Bichenkov, George Mateo, Emad M.M. Kassem, Gehan H. Hegazy, Magid Abou-Gharbia, Wayne Childers. Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Ka/mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters (2017) 27:3117–3122.

6. Somaia S. Abd El-Karim, Manal M. Anwar, Eman R. Zaki, Samia A. Elseginy Zienab M. Nofal. Synthesis and molecular modeling of new benzimidazoles as glutathione S-transferase inhibitors and anticancer agents. Future Medicinal Chemistry. 10 (2018) 157-181.

7. Kamelia M. Amin, Yasmin M. Syam, Manal M. Anwar, Hamed I. Ali, Tamer M. Abdel- Ghani, Aya M. Serry. Synthesis and molecular docking study of new benzofuran and furo[3,2-g]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors. Bioorganic Chemistry (2018), 76:487–500.

8. Somaia S. Abd El-Karima, Manal M. Anwara, Yasmin M. Syam, Manal A. Nael, Hanan F. Ali, Mohamed A. Motaleb. Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies. Bioorganic Chemistry (2018), 81:481–493.

9. Yasmin M. Syam, Somaia S. Abd El-Karim, Tamer Nasr, Samia A. Elseginy, Manal M. Anwar, Mohsen M. Kamel, Hanan F. Ali. Design, Synthesis and Biological Evaluation of Spiro Cyclohexane-1,2-Quinazoline Derivatives as Potent Dipeptidyl Peptidase IV Inhibitors. Mini-Reviews in Medicinal Chemistry 19 (3) (2019) 250-269.
DOI: 10.2174/1389557517666170828121018.

10. Manal M. Anwar, Somaia S. Abd El-Karim, Ahlam H. Mahmoud, Abd El-Galil E. Amr, Mohamed A. Al-Omar, A Comparative Study of the Anticancer Activity and PARP-1 Inhibiting Effect of Benzofuran–Pyrazole Scaffold and Its Nano-Sized Particles in Human Breast Cancer Cells. Molecules 24 (2019) 2413. doi:10.3390/molecules24132413.

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