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Member Profile

Membership type: full

Chima Ekeleme

Country of origin: Nigeria Currently in: Nigeria, Abakaliki General field of specialization: Structural, Cell and Molecular Biology
Academic Background


2015 Doctorate Medical and Health Sciences incl Neurosciences
2010 Master Medical and Health Sciences incl Neurosciences
2005 Undergraduate Structural, Cell and Molecular Biology
Research and Profession

Current Research Activities

Structural, Cell and Molecular Biology

Nutraceuticals and functional foods in the prevention and management of diseases

Publications resulting from Research: 

2. Famurewa, A.C., Ekeleme-Egedigwe, C.A., Onwe,C.S., Egedigwe, U.O., Okoro, C.O., Egedigwe, U.J and Asogwa, N.T.(2020). Ginger juice prevents cisplatin-induced oxidative stress, endocrine imbalance and NO/iNOS/ NF-KB signaling via modulating testicular redox-inflammatory mechanism in rats. Andrologia http.// and.13786

3. Ekeleme-Egedigwe, C.A., Famurewa, A.C., David, E.E., Eleazu, C.O., Egedigwe, U.O. (2020). Antioxidant potential of garlic oil supplementation prevents cyclophosphamide-induced oxidative testicular damage and endocrine depletion in rats. Journal of Nutrition & Intermediary Metabolism 18: 100109 DOI:org/10.1016/jnim.2020.100109

4. Famurewa A.C., Akunna, G.G, Nwafor J, Chukwu O.C, Ekeleme-Egedigwe C.A. and Oluniran J.N.(2020) Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats. Avicenna Journal of Phytomedicine. 10(3):316-324

5. Famurewa, A.C., Ekeleme – Egedigwe, A.C., David, E.E., Eleazu, C.O., Folawiyo, A.M. and Obasi, N.A (2019): Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signaling, and caspase-3-dependent apoptosis in female rats. Toxicology Mechanisms and Methods,1-9 DOI:10.1080/15376516.2019.1669243

6. Famurewa, A.C., Asogwa, N.T., Aja, P.M., Akunna, G.G., Awoke, J.N., Ekeleme-Egedigwe, C.A., Maduagwuna, E.K., Folawiyo, A.M., Besong, E.E., Ekpono, E.U. and Nwoha, P.A. (2019). Moringa oleifera seed oil modulates redox imbalance and iNOS/NF-ĸB/caspase-3 signaling pathway to exert antioxidant, anti-inflammatory and antiapoptotic mechanisms against anticancer drug 5-fluorouracil-induced nephrotoxicity in rats. South African Journal of Botany, 127: 96–103.

7. Eleazu, C.O., Ekeleme-Egedigwe, C.A., Famurewa, A.C., Mohamed, M., Akunna G, David E, Nwofe B., Chukwu, F., Amakor, P., A., Ayogu, C., Onuoha W., Olamide N, Achi, N.K., Emelike, U. (2019). Modulation of the lipid profile, hepatic and renal antioxidant activities, and markers of hepatic and renal dysfunctions in alloxan-induced diabetic rats by virgin coconut oil. Endocrine, Metabolic & Immune Disorders- Drug Targets. 19(7):1032-1040 DOI:10.2174/1871530319666190119101058

8. Achi,N.K., Onyeabo,C., NnateD.A., Ekeleme-Egedigwe,C.A., Kalu, I.K., Chibundu, I.C. and Wokoma, G.C. (2018). Therapeutic effects of Azadirachta indica A. Juss. leaves in malaria-induced male Wistar rats. Journal of Pharmacy & Pharmacognosy Research, 6(3):191-204

9. Ohaegbu, C.G., Achi, N.K., Asamudo, N.U., Nnate, D.A., Oriaku, E.C. and Ekeleme-Egedigwe, C.A. (2018). Preliminary biochemical investigation of bioactive compounds and antibiofilm activity of Ocimum gratissimum against food-borne microorganisms. Carpathian Journal of Food Science and Technology, 10(1):19-34

10. Wang, G., Ekeleme-Egedigwe, C.A., El Hamdouchi, A., Sauciuvenaite, J., Bissland, R., Djafarian, K., Ojiambo, R., Ramuth, H., Holasek, S., Lackner, S., Diouf, A., Hambly, C., Vaanholt, L. M., Cao, M., Hacker, M., Kruger, H.S., Seru, T., Faries, M.D. and Speakman, J.R. (2018). Beauty and the Body of the Beholder: Raters’ BMI Has Only Limited Association with Ratings of Attractiveness of the Opposite Sex. Obesity, 26(3): 522–530. doi:10.1002/oby.22092

11. Ebokaiwe, P.A., Omaka, O.N., Okorie, U.C., Oje, O.A., Egedigwe, C.A., Ekwe, A. and Nnaji, N.A.(2018). Assessment of heavy metals around Abakaliki metropolis and potential bioaccumulation and biochemical effects on the liver, kidney and erythrocyte of rats. Human and Ecological Risk Assessment: An International Journal, 24(5):1233-1255, DOI: 10.1080/10807039.2017.1410695

12. Eleazu, C.O., Abagha S., Sani, S. Eleazu K.C. and Egedigwe-Ekeleme, C.A. (2018). Starch digestibility, polyphenol contents and in vitro alpha amylase inhibitory properties of two varieties of cocoyam (Colocassia esculenta and Xanthosoma mafafa) as affected by cooking. Journal of Food Measurement and Characterization, 1-7

13. Famurewa, A.C., Ekeleme-Egedigwe, C.A., Nwali, S.C., Agbo, N.N., Obi, J.N., Ezechukwu, G.C. (2018). Dietary supplementation of virgin coconut oil improves lipid profile and hepatic antioxidant status and potential benefits on cardiovascular risk indices in normal rats. Journal of Dietary Supplements, 15 (3): 330-342. http: doi10.1080/19390211.2017.1346031

Current profession

Current professional activities type: 
Currently, I teach and supervise students both at the Undergraduate and Post graduate levels. Also, research works are carried out and supervised by me.

Workshop and Conference Attended

2021 Michael Okpara University of Agriculture, Umudike, Umuahia Abia State 5th Biennal iInternational conference of OWSD- NIGERIA
2012 Cape Town, South Africa Advanced Summer School on Nutrition and Disease: Biochemical and molecular Insights
2012 Alexandria, Egypt Sixth International Biennial Conference of Academy of Sciences for the Developing World/BiovisionAlexandria.NXT 2012 (TWAS/BVA.NXT 2012) Program) at the Bibliotheca Alexandrina . Theme: New Life Sciences: Linking Sc
Prizes, Grants and Awards

Other Awards

Sep 2003
Monetary Award
Nigerian Women in Georgia awarded a monetary scholarship to sophomores in all Nigerian universities.I was a recipient of the award from Abia State in Nigeria
OWSD 6th General Assembly certificate: download

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