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Membership type: full

May El-Manawaty

Country of origin: Egypt Currently in: Egypt, Cairo General field of specialization: Biological Systems and Organisms
Academic Background


2018 Doctorate Biological Systems and Organisms
Research and Profession

Current Research Activities

Biological Systems and Organisms

Working on plant drug discovery in the fields of anticancer/cytotoxicity (using human tumour cell lines and MTT method), anticandida, radical scavenging activity (DPPH), brine shrimp cytotoxicity, schistosomicidal activity, anticancer/proapoptopic activity (using M30 kits). Working on plant fractionation and chromatography.

Publications resulting from Research: 

1. El Manawaty, M.A., Fayad, W., El-Fiky, N.M., Wassel, G.M., El-Menshawi, B.S., 2013, High-throughput screening of 75 euphorbiaceae and myrtaceae plant extracts for in-vitro antitumor and pro-apoptotic activities on human tumor cell lines, and lethality to brine shrimp, International Journal of Pharmacy and Pharmaceutical Sciences, 5 (SUPPL. 2), pp. 178-183.

2. Bassem S El-Menshawi, Walid Fayad, Khaled Mahmoud, Salwa M El-Hallouty, May El-Manawaty, Maria Hägg Olofsson, Stig Linder, 2010. Screening of natural products for therapeutic activity against solid tumors, Indian Journal of Experimental Biology, Volume 48, Issue 3, Pages 258-264.

3. Yousif, F., Wassel, G,, Boulos, L., Labib, T., Mahmoud, K., El-Hallouty, S., El Bardicy, S., Mahmoud, S., Ramzy, F., Gohar, L., El-Manawaty, M., El Gendy, M.A.M., Fayad, W., El-Menshawi, B., 2012, Contribution to in vitro screening of Egyptian plants for schistosomicidal activity, Pharmaceutical Biology, Volume 50, Issue 6, Pages 732-739.

4. Mamdouh, A.A.Hammouda, FatmaAbdAleem, A. El-Hag, Weam S. El-Serwy and El-Manawaty, M.A., 2015, Synthesis and characterization of new fused 4H-pyranquinoline carbonitrile derivatives with anticipated antitumor biological activity. Research Journal of Pharmaceutical, biological and chemical sciences, volume 6, Issue 1, pages 200-208.

5. Yousif, F, Hifnawy, M S, Soliman, G, Boulos, L, Labib, T, Mahmoud, F, Ramzy, F, Yousif, M, Hassan, I, Mahmoud, K, El-Hallouty, S M, El Gendy, M, Gohar, L, El- Manawaty, M, Fayyad, W, El-Menshawi, B S., 2007. Large-scale in vitro screening for schistosomicidal activity of Egyptian Native and cultivated plants. Pharmaceutical Biology, 45(6), pp. 501-510.

6. SM Bassem, W Fayad, M Khaled, SM Hallouty, M Manawaty, MH Olofsson, S Linder, 2010. Antiproliferation effects of Sophopra japonica.

7. D.A. Osman, M.E., Eid, M.M., Khattab, O.H., El-Hallouty, S.M., El-Manawaty, M., Mahmoud, D.A. 2015. In vitro cytotoxicity of biosynthesized Ag/CS NP against MCf7, PC3 and A549 cancer cell lines. International Journal of PharmTech Research, Vol. 8, issue 5, pp. 1011-1017.

8. Afaf KE El-Ansary, Neama A Mohamed, Khaled O Mohamed, Hend MW Abd-Elfattah and Mai El-Manawaty 2015. A Simple and Convenient Synthesis of Novel Thiopyrimidine Derivatives as Anticancer Agents. Research Journal of Pharmaceutical, Biological and Chemical Sciences, volume 6, issue 4, pp. 1745-1752.

9. Seham S El-Hawary, Khaled M Hanafy, Gamila M Wasel, Bassem M Menshawi, Lamiaa H Gohar, May A El-Manawaty, 2015. Comparative Evaluation of the Phenolic and Flavonoid Contents, Free Radical-Scavenging Potencies and Cytotoxic Activities of Six Species Belonging to Family Salicaceae. International journal of pharmacognosy and phytochemistry, volume 30, issue 1, pp. 1313-1318.
10. Fahmy, H.H., Srour, A.M., Ismail, M.A., Khater, M.A., Serrya, R.A. and El-Manawaty, M.A., 2016. Design and synthesis of some new tri-substituted pyrazole derivatives as anticancer agents. Research on Chemical Intermediates, pp.1-12.
11. Ismail, N.S., George, R.F., Serya, R.A., Baselious, F.N., El-Manawaty, M., Shalaby, E.M. and Girgis, A.S., 2016. Rational design, synthesis and 2D-QSAR studies of antiproliferative tropane-based compounds. RSC Advances, 6(104), pp.101911-101923.

12. Fayad, W., Salwa, M., El-Manawaty, M.A., Mounier, M.M., Soliman, A.A., Yousry, A.A., Farghaly, A.A., Fahmy, M.A., Hasasn, Z.M., Linder, S. and Mahmoud, K., 2017. A systematic multicellular spheroids screening approach lead to the identification of antineoplastic activity in three different plant extracts from the Egyptian flora. Journal of Applied Pharmaceutical Science Vol, 7(06), pp.013-022.

13. El-Serwy, W.S., El-Hag, F.A.A.A., Hammouda, M.A.A., El-Manawaty, M.A., El-Rashedy, A.A. 2016. Synthesis, docking and pharmacological evaluation of some new quinoline derivatives. International Journal of Pharmacy and Technology, vol. 8 (4), pp. 25221-25236.

14. Wael A. El-Sayed , Ashraf M. Mohamed, Hemat S. Khalaf , Dina S. EL-Kady , May Al-Manawaty, 2017. Synthesis, Docking Studies and Anticancer Activity of New Substituted Pyrimidine and Triazolopyrimidine Glycosides. Journal of Applied Pharmaceutical Science, Vol. 7 (09), pp. 001-011.
15. Srour, A.M., Fahmy, H.H., Khater, M.A., El-Manawaty, M.A., Shalaby, E.S.M. 2018. Synthesis, characterization, and cytotoxic activity of some new 1,3,4-trisubstituted pyrazoles against diverse tumor cell lines. Monatshefte fur Chemie, 149(6), pp. 1137-1147.
16. Elzahabi, H.S.A., Nossier, E.S., Khalifa, N.M., Alasfoury, R.A., El-Manawaty, M.A. 2018. Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry, 33(1), pp. 546-557.
17. El-Manawaty, M.A., Gohar, L. 2018. In vitro alpha-glucosidase inhibitory activity of egyptian plant extracts as an indication for their antidiabetic activity. Asian Journal of Pharmaceutical and Clinical Research, 11(7), pp. 360-367.
18. Eid, M.M. , El-Hallouty, S.M., El-Manawaty, M., Abdelzaher, F.H., Al-Hada, M., Ismail, A.M. 2018. Preparation conditions effect on the physico-chemical properties of magnetic–plasmonic core–shell nanoparticles functionalized with chitosan: Green route. Nano-Structures and Nano-Objects, 16, pp. 215-223.
19. Waill A. Elkhateeb et al. 2018. Cytotoxicity and Hypoglycemic Effect of the Japanese Jelly Mushroom Auricularia auricula-judae. Chemistry Research Journal, 3(4). pp. 123-133.
20. Aladdin M Srour et al. 2018. Synthesis & molecular modeling studies of bronchodilatory active indole-pyridine conjugates. Future Medicinal Chemistry, 10(15), pp. 1787-1804.

Current profession

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