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Membership type: full

Rana Obaidat

Country of origin: Jordan Currently in: Jordan, Amman General field of specialization: Medical and Health Sciences incl Neurosciences
Academic Background


2004 Doctorate Medical and Health Sciences incl Neurosciences
1999 Master Medical and Health Sciences incl Neurosciences
1996 Undergraduate Medical and Health Sciences incl Neurosciences
Research and Profession

Current Research Activities

Medical and Health Sciences incl Neurosciences

Pharmaceutical Technology

Publications resulting from Research: 

1) Rana Obaidat, Haneen Aleih, Hadeia Mashaqbeh, Bashar Altaani, M Alsmadi
Mo’tasem, Mohammad Alnaief. Development and evaluation of cocoa butter taste masked ibuprofen using supercritical carbon dioxide. AAPS PharmSciTech 2021, 22 (3):1-13.
2) Mohammad Alnaief, Rana Obaidat, Mo’tasem M. Alsmadi. Preparation of Hybrid Alginate-Chitosan Aerogel as Potential Carriers for Pulmonary Drug Delivery Polymers 2020, 12(10), 2223;
3) Bashar Al-Taani, Rana Obaidat, Wala Malkawi. Enhancement of Dissolution of Atorvastatin through Preparation of Polymeric Solid Dispersions Using Supercritical Fluid Technology. Res. Pharm. Sci. 2020 Apr; 15(2): 123–136.
4) Mo’tasem M. Alsmadi, Rana M. Obaidat, Mohammad Alnaief, Borhan Aldeen Albiss, Nabil Hailat. Development, In-Vitro Characterization and In-Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment. AAPS PharmSciTech. 2020.
5) Rana M Obaidat, Mai Khanfar, Rand Ghanma. A Comparative Solubility Enhancement Study of Cefixime Trihydrate Using Different Dispersion Techniques. AAPS PharmSciTech, 20(5):194. 2019. DOI: 10.1208/s122490191395-y.
6) Rawda Yaseen AlSheyyab, Rana Mohammad Obaidat, Yara Radi Altall, Rana Talal Abuhuwaij, Rand Radwan Ghanma, Anoud Sameer Ailabouni, Hadeia Ahmad Mashaqbeh, Shayma Al-Haj. Solubility enhancement of nimodipine through preparation of Soluplus® dispersions. Journal of Applied Pharmaceutical Science, Vol. 9(09), pp 030-037, September, 2019. DOI: 10.7324/JAPS.2019.90905
7) M Alnaief, R Obaidat, H Mashaqbeh. Loading and evaluation of meloxicam and atorvastatin in carrageenan microspherical aerogels particles. Journal of Applied

Pharmaceutical Science, Vol. 9(01), pp 083-088, 2019. DOI:
8) Rana Obaidat, Mohammed Alnaief, Hadeia Mashagbeh. Investigation of Carrageenan aerogel microparticles as potential drug carrier. AAPS PharmSciTech, July 2018, volume 19, Issue 5, 2226-2236.
9) Rana Obaidat, Mohammed Alnaief & Philip Jaeger. Significant solubility of carbon dioxide in Soluplus® facilitates impregnation of ibuprofen using supercritical fluid technology, Pharmaceutical Development and Technology, (2018) , 23:7,
697705, DOI: 10.1080/10837450.2017.1315135
10) Mohammad Alnaief, Rana Obaidat, Hadeia Mashaqbeh. Effect of processing parameters on preparation of carrageenan aerogel microparticles. Carbohydrate polymers, 2018. DOI: 10.1208/s12249-018-1021-4.
11) Nizar A. Al-Shar’i , and Rana M. Obaidat. Experimental and Computational Comparative Study of the Supercritical Fluid Technology (SFT) and Kneading
Method in Preparing β-Cyclodextrin Complexes with Two Essential Oils (Linalool and Carvacrol). AAPS PharmSciTech, 2018 Apr;19(3):1037-1047. doi: 10.1208/s12249-017-0915-x. Epub 2017 Nov 13.
12) AlSheyyab RY, Al-Taani BM, Obeidat RM, Alsmadi MM, Masaedeh RK, Sabat RN. Delivery of peptidic Gonadotropin Releasing Hormone Antagonists, Curr Drug Deliv. 2018:15 (15):602-609. doi: 10.2174/1567201815666180214142300.
13) Rafeef Masadeh, Rana Obaidat, Mo'tasem Alsmadi1, Bashar Altaani1, Mai
Rawda Alshyab, Mohammed Qaoud. Technical Insight of biodegradable Polymers Used in Implants, Jordan Journal of Pharmaceutical Sciences, Accepted for publication January 15th 2018.
14) Mohammad Alnaief, Rana Obaidat, Hadeia Mashaqbeh, Effect of processing parameters on preparation of carrageenan aerogel microparticles, Carbohydrate Polymers, Volume 180, 15 January 2018, Pages 264-275, ISSN 0144-8617,
15) AlSheyyab, Rawda Y.; Al-Taani, Bashar M.; Obeidat, Rana M.; Alsmadi, Motasem M.; Masaedeh, Rafeef K.; Sabat, Raghda N. Delivery of Peptidic Gonadotropin
Releasing Hormone Antagonists. Current Drug Delivery, Volume 15, Number 5, 2018, pp. 602-609(8).
16) Rana Obaidat, Bashar Al-Taani, Hanan Al-Quraan. Effect of Selected Polymers on Dissolution and Stabilization of Amorphous Form of Meloxicam. International Journal of Pharmacy and Pharmaceutical Sciences, 9 (9): 33-424, 2017.
17) Gubran Khalil Mohammed, Rana M. Obaidat, Shereen Assaf, Mai Khanfar, Bashar Al-Taani. Formulations and Technologies in Growth Hormone Delivery.
International Journal of Pharmacy and Pharmaceutical Sciences, 9 (7): 1-12, 2017.
18) Rana M. Obaidat, Bashar AlTaani, Anoud Ailabouni. Effect of Different
Dispersions on In-Vitro Dissolution rate and Stability of Celecoxib Class II Drug.
Journal of Polymer Research.24 (58): 1-14, 2017. DOI 10.1007/s10965017-1215-6
19) Rana M. Obaidat, B Tashtoush, A Shwayyat, Enhancement of Tacrolimus Dissolution through Preparation of Solid Dispersions. Lat. Am. J. Pharm. 36 (2): 35565 (2017).
20) Rana M. Obaidat, N Al-Shar'i, B Tashtoush, T Athamneh, Pharmaceutical
Development and Technology, 1, 1-12, 2016. DOI:
21) Rana M. Obaidat , Bassam M. Tashtoush, Alaa Abu Awad, and Rana T. Al Bustami. Using Supercritical Fluid Technology (SFT) in Preparation of Tacrolimus Solid Dispersions AAPS PharmSciTech ( 2016). DOI: 10.1208/s12249-0160492-4.
22) Rana M. Obaidat, Bassam M. Tashtoush, Mohammad F. Bayan, Rana T. Al Bustami, and Mohammad Alnaief. Drying using supercritical fluid technology as a potential method for preparation of chitosan aerogel microparticles. AAPS PharmSciTech, 12 March 2015. doi: 10.1208/s12249-015-0312-2.
23) Rana Obaidat, Darryl Yu, Steve Aljawhiri and Robert Macgregor Jr. Moderate hydrostatic pressure–temperature combinations for inactivation of Bacillus subtilis spores. High Pressure Research, May 2015. doi:
24) Rana M Obaidat, Ammar Bader, Wafa Al-Rajab, Aiman Obaidat, and Ghassan Abu Sheikha. Preparation of mucoadhesive oral patches of Tetracycline hydrochloride and Carvacrol: A promising novel oral combination for local mouth bacterial infections and Candidiasis. Sci Pharm., 79, 179-212, 2011. doi:10.3797 / scipharm.1004-18. ISSN: 0036-8709.
25) Kamal Sweidan, Abdel-Motalleb Jaber , Nawzat Al-jbour, Rana Obaidat, Mayyas Al-Remawi, Adnan Badwan. Further investigation on the degree of deacetylation of chitosan determined by potentiometric titration. Journal of Excipients and Food Chemicals, 2 (1), 16-24, 2011. ISSN number: 2150-2668.
26) Aiman A. Obaidat, Rana M. Obaidat. Development and evaluation of fastdissolving tablets of meloxicam-β-cyclodextrin complex prepared by direct compression. Acta Pharmaceutica. 61, 83-91, 2011. ISSN 1330-0075, eISSN
27) Rana Abu-Huwaij, Rana M Obaidat, Kamal Sweidan, and Yusuf Al-Hiari. Formulation and in vitro evaluation of xanthan gum/carbopol 934-based mucoadhesive patches, loaded with nicotine, AAPS PharmSciTech, 1-7, 2010. doi:
10.1208/S12249010-9534-5. ISSN: 15309932.
28) Rana Obaidat, Nawzat Al-Jbour, Khaldoun Al-Sou’d, Kamal Sweidan, Mayyas AlRemawi, Adnan Badwan. Some physicochemical properties of low molecular weight chitosans and their relationship to conformation in aqueous solution. J Solution Chem, 39, 575–588, 2010. ISSN: 0095-9782, eISSN: 1572-8927.
29) Rana M Obaidat, Kamal Sweidan,Wafa Al-Rajab, Mai Khanfar, Rana AbuHwaij. Development of local, mucoadhesive, sustained release patches of tetracycline hydrochloride for treatment of mouth infections: a preliminary in vitro study.
European Journal of Parenteral & Pharmaceutical Sciences, 15(4): 87-94, 2010. ISSN:
30) Shereen Assaf, Mai Khanfar, Rana Obaidat, Mutaz S. Salem, and Adi Areeda, Effect of Different Organic solvents on crystal habits of mefanimic acids, Jordan Journal of Pharmaceutical Sciences, 2 (2), 150-158, 2009. ISSN: 1995-7157.
31) Rana Obaidat, Khouloud A. Alkhamis, Mutaz S. Salem, Determination of Factors Affecting Kinetics of Solid State Transformation of Fluconazole Polymorph II to
Polymorph I Using Diffuse Reflectance Fourier Transform Infrared Spectroscopy. Drug Development and Industrial Pharmacy, 36 (5): 570-580, May, 2010. ISSN:
32) Khouloud A. Alkhamis, Mutaz S. Salem, Rana Obaidat, Comparison Between Dehydration and Desolvation Kinetics of Fluconazole Monohydrate and Fluconazole Ethylacetate solvate Using Three Different Methods. Journal of Pharmaceutical Sciences, 95 (4), 859-870, 2006. ISSN: 1520-6017.
33) Mino R. Caira, Khouloud A. Alkhamis, Rana M. Obaidat, Preparation and crystal characterization of a polymorph, a monohydrate, and an ethyl acetate solvate of the antifungal fluconazole, Journal of Pharmaceutical Sciences, 93 (3), 601-611, 2004. ISSN: 1520-6017.
34) Aiman A. Obaidat, Rana M. Obaidat, Controlled release of tramadol hydrochloride from matrices prepared using glyceryl behenate, European Journal of Pharmaceutics and Biopharmaceutics, 52, 231235, 2001. ISSN: 0939-6411.


a Rana M. Obaidat, Adnan Badwan. US Patent. Process of Producing and Method of
Using Soluble High Molecular-Weight Chitosan. Issued January 9th , 2018. Application Number is 15413942. US9862780B1 - Process of producing and method of using soluble high molecular-weight chitosan - Google Patents

b Faisal Al-Akayleh, Mayyas Rimawi, Rana M. Obaidat. A Pharmaceutical composition of Fentanyl and one or more fatty acids, and a method of preparation thereof, 2020, PCT/JO2020050011.

Current profession

Current professional activities type: 
Higher Education Study
Professor of Pharmaceutical Technology

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