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Membership type: full

Adebola Oyedeji

Country of origin: Nigeria Currently in: South Africa, Mthatha General field of specialization: Chemical Sciences
Academic Background

Degrees

2003 Doctorate Chemical Sciences
1990 Master Chemical Sciences
Research and Profession

Current Research Activities

Chemical Sciences

A) Chemical composition and biological evaluation of Cannabis B) Bioprospecting on plant for antipile potential C) Comprehensive qualitative and quantitative chemical analyses of the essential oil of some economically and medicinally useful plants 1. Isolation and elucidation of novel compounds from the essential oils of interest. 2. Qualitative and quantitative biological studies of “weeds” essential oil bearing plants for medicinal and insecticidal potential. D) Investigations of the ethnomedicinal claims on the medicinal plants through bioassay; and Isolation and elucidation of bioactive compound for possible drug formulation. E) Investigation of on bioactive compounds isolated from Eastern Cape medicinal plants used predominantly by traditional healers for nano-therapy. F) Investigation of some Eastern Cape medicinal plants for medical devices formulation.


Publications resulting from Research: 


Dambuza A, Rungqu P, Oyedeji AO, Miya G, Oriola AO, Hosu YS and Oyedeji OO (2024). Therapeutic Potential of Pectin and Its Derivatives in Chronic Diseases. Molecules, 2024, 29, 896. https://doi.org/10.3390/ molecules29040896
Ogundele SB, Oriola AO, Oyedeji AO, Asiyanbola ID, Agbebi EA, Olubiyi OO, Olorunmola FO. Babalola K. Yusuf BA and Agbedahaunsi JH (2023). Antiplasmodial Activity of Chemical Constituents of Artocarpusaltilis (Parkinson ex F.A.Zorn) Fosberg Stem Bark: An Experimental-cum-Computational Investigation. Eur. Chem. Bull. 2023, 12(10), 11411-11436. Doi: 10.48047/ecb/2023.12.10.806
Miya GM, Oriola AO, Payne B, Cuyler M, Lall N, Oyedeji AO (2023). Steroids and Fatty Acid Esters from Cyperus sexangularis Leaf and Their Antioxidant, AntiInflammatory and Anti-Elastase Properties. Molecules 2023, 28, 3434. https://doi.org/10.3390/ molecules28083434
Okot DF, Namukoba J, Vudriko P, Anywar G, Heydenreich M, Oyedeji AO, Byamukama R (2023). In Vitro Anti-Venom Potentials of Aqueous Extract and Oils of Toona ciliata M. Roem against Cobra Venom and Chemical Constituents of Oils. Molecules 2023, 28(7), 3089; https://doi.org/10.3390/molecules28073089
Oriola AO, Aladesanmi AJ, Idowu TO, Akinkunmi EO, Adebola O. Oyedeji AO, Ogunsina MO, Arthur G, Schweizer F (2022). Saponin from Massularia acuminata inhibits the Growths of Some Microbial and Human Cancerous Cells in vitro. Chemistry Africa, https://doi.org/10.1007/s42250-022-00488-0
Jaquilin RPJ, Oluwafemi SO, Sabu T and Oyedeji AO (2022). Recent advances in drug delivery nanocarriers incorporated in temperature-sensitive Pluronic F-127–A critical review. Journal of Drug Delivery Science and Technology, 72 (2022) 103390 https://doi.org/10.1016/j.jddst.2022.103390
Kerebba N, Oyedeji AO, Byamukama R, Kuria SK, Oyedeji OO (2022). UHPLC-ESI-QTOF-MS/MS Characterisation of Phenolic Compounds from Tithonia diversifolia (Hemsl.) A. Gray and Antioxidant Activity. Biological Chemistry & Chemical Biology: Chemistry Select, 2022, 7, e202104406, 1-16, 2022, 12, 77-93 DOI: doi.org/10.1002/slct.202104406
Odieka, A.E.; Obuzor, G.U.; Oyedeji, O.O.; Gondwe, M.; Hosu, Y.S.; Oyedeji, A.O (2022). The Medicinal Natural Products of Cannabis sativa Linn.: A Review. Molecules 2022, 27, x. https://doi.org/10.3390/molecules27051689
Oyemitan IA, Elusiyan CA, Onifade AO, Akanmu MA, Oyedeji AO, McDonald AG (2017) Neuropharmacological profile and chemical analysis of fresh rhizome essential oil of Curcuma longa (turmeric) cultivated in Southwest Nigeria. Toxicology Reports, 4, 391–398. DOI: 10.1016/j.toxrep.2017.07.001
Avoseh O, Oyedeji O, Rungqu P, Nkeh-Chungag B, Oyedeji A (2015) Cymbopogon Species; Ethnopharmacology, Phytochemistry and the Pharmacological Importance, Molecules 2015, 20, 7438-7453; doi:10.3390/molecules20057438. http://www.mdpi.com/1420-3049/20/5/7438



Current profession

Current professional activities type: 
Research
Teaching
Prof (Dr) Adebola Oyedeji leads a vibrant natural product research group with over 15 M and D students. She is a C2 NRF-rated scientist and has over 150 SAPSE-published articles. Her research hinges on medicinal plants (natural products chemistry) with a special interest in inaugurating the link between chemistry and the ethnomedicinal claim of the plant being used in traditional medicine and communities. She has isolated several compounds, some of which were further derivatized and evaluated for their potency as anticancer (breast cancer), anti-inflammatory, anti-gonorrhoea, antibacterial to mention a few. She continues to study the South African essential oil-bearing plants to establish the various chemotypes for commercialization. Her study on turning citrus waste into products for postharvest preservation and management of human ailments. Her passion is in the product development of her laboratory research into prototypes.

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