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Jyoti Rajan Sharma

Country of origin: India Currently in: South Africa, Cape Town General field of specialization: Structural, Cell and Molecular Biology
Academic Background


2010 Doctorate Structural, Cell and Molecular Biology
Research and Profession

Current Research Activities


1) To investigate the functional and clinical significance of genetic variants that contribute towards multifarious treatment outcomes in a black South African cohort with uncontrolled hypertension (UHTN). 2) Currently, I am also involved in a SAMRC/BRIP’s SARS-Co-V2 wastewater surveillance program that aims to determine the spatial and temporal SARS-CoV-2 trends, during COVID-19 peak in the Western Cape. Biography (<200 words): Currently, my research focus is on the identification and validation of new population specific molecular targets for disease prognosis, diagnosis, and novel therapeutic development. The years of experience in diverse research fields has enriched my understanding of disease biology from various perspectives and enhanced my capability to device and execute multidisciplinary projects. I would like to implement this experience to devise new strategies and develop new technologies/methodologies that will accelerate human genetics research efforts. I have published 21 research articles in the peer reviewed journals.

Publications resulting from Research: 

1. Renée Street *, Angela Mathee , Noluxabiso Mangwana, Stephanie Dias Jyoti Rajan Sharma, et al. Spatial and Temporal Trends of SARS-CoV-2 RNA from Wastewater Treatment Plants over 6 Weeks in Cape Town, South Africa (published International Journal of Environmental Research and Public Health (IF 2.8)
2.Sihle Mabhida, Lebohang Mashatola, Mandeep Kaur, Jyoti Sharma, Teke Apalata, Babu Muhamed, Mongi Benjeddou, Rabia Johnson. Hypertension in African Population: A Systematic Review (Genes) 21, 12.

3. Jyoti Rajan Sharma, Sihle E. Mabhida, Bronwyn Myers, Teke Apalata, Edward Nicol, Mongi Benjeddou, Christo Muller, and Rabia Johnson. Prevalence of Hypertension and its associated risk factors in a rural black population of Mthatha town, South Africa. Int. J. Environ. Res. Public Health 2021, 18, 1215.

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