Degrees:
2016
Catherine Kegakilwe Koofhethile > Degrees
Medical and Health Sciences incl Neurosciences
Publications resulting from Research
1. Undetectable proviral deoxyribonucleic acid in an adolescent perinatally infected with human immunodeficiency virus-1C and on long-term antiretroviral therapy resulted in viral rebound following antiretroviral therapy termination: A case report with implications for clinical care.
Koofhethile CK, Moyo S, Kotokwe KP, Mokgethi P, Muchoba L, Mokgweetsi S, Gaolathe T, Makhema J, Shapiro R, Lockman S, Kanki P, Essex M, Gaseitsiwe S, de Oliveira T, Novitsky V. Medicine (Baltimore). 2019 Nov;98(47):e18014. doi: 10.1097/MD.0000000000018014. PMID: 31764816 Free Article
2. CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. Koofhethile CK, Ndhlovu ZM, Thobakgale-Tshabalala C, Prado JG, Ismail N, Mncube Z, Mkhize L, van der Stok M, Yende N, Walker BD, Goulder PJR, Ndung'u T. J Virol. 2016 Jul 11;90(15):6818-6831. doi: 10.1128/JVI.00276-16. Print 2016 Aug 1. PMID: 27194762 Free PMC Article
3. CD8+ TCR Bias and Immunodominance in HIV-1 Infection.
Kløverpris HN, McGregor R, McLaren JE, Ladell K, Harndahl M, Stryhn A, Carlson JM, Koofhethile C, Gerritsen B, Keşmir C, Chen F, Riddell L, Luzzi G, Leslie A, Walker BD, Ndung'u T, Buus S, Price DA, Goulder PJ. J Immunol. 2015 Jun 1;194(11):5329-45. doi: 10.4049/jimmunol.1400854. Epub 2015 Apr 24. PMID: 25911754 Free PMC Article
4. Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load. Kløverpris HN, McGregor R, McLaren JE, Ladell K, Stryhn A, Koofhethile C, Brener J, Chen F, Riddell L, Graziano L, Klenerman P, Leslie A, Buus S, Price DA, Goulder P. AIDS. 2014 Sep 10;28(14):2007-21.
PMID: 24906112 Free PMC Article
5. Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. J Virol. 2014 May;88(9):4668-78. doi: 10.1128/JVI.03303-13. Epub 2014 Feb 5. PMID: 24501417 Free PMC Article
6. Mosaic HIV-1 Gag antigens can be processed and presented to human HIV-specific CD8+ T cells.
Ndhlovu ZM, Piechocka-Trocha A, Vine S, McMullen A, Koofhethile KC, Goulder PJ, Ndung'u T, Barouch DH, Walker BD. J Immunol. 2011 Jun 15;186(12):6914-24. doi: 10.4049/jimmunol.1004231. Epub 2011 May 16. PMID: 21576505 Free PMC Article
7. HLArestrictor--a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides. Erup Larsen M, Kloverpris H, Stryhn A, Koofhethile CK, Sims S, Ndung'u T, Goulder P, Buus S, Nielsen M.
Immunogenetics. 2011 Jan;63(1):43-55. doi: 10.1007/s00251-010-0493-5. Epub 2010 Nov 16. PMID: 21079948
8. Prevalence and potential pathogenicity of Vibrio parahaemolyticus in Chinese mitten crabs (Eriocheir sinensis) harvested from the River Thames estuary, England. Wagley S, Koofhethile K, Rangdale R. J Food Prot. 2009 Jan;72(1):60-6. PMID: 19205465
9. Comparison of V. parahaemolyticus isolated from seafoods and cases of gastrointestinal disease in the UK.
Wagley S, Koofhethile K, Wing JB, Rangdale R. Int J Environ Health Res. 2008 Aug;18(4):283-93. doi: 10.1080/09603120801911064. PMID: 18668416
Koofhethile CK, Moyo S, Kotokwe KP, Mokgethi P, Muchoba L, Mokgweetsi S, Gaolathe T, Makhema J, Shapiro R, Lockman S, Kanki P, Essex M, Gaseitsiwe S, de Oliveira T, Novitsky V. Medicine (Baltimore). 2019 Nov;98(47):e18014. doi: 10.1097/MD.0000000000018014. PMID: 31764816 Free Article
2. CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. Koofhethile CK, Ndhlovu ZM, Thobakgale-Tshabalala C, Prado JG, Ismail N, Mncube Z, Mkhize L, van der Stok M, Yende N, Walker BD, Goulder PJR, Ndung'u T. J Virol. 2016 Jul 11;90(15):6818-6831. doi: 10.1128/JVI.00276-16. Print 2016 Aug 1. PMID: 27194762 Free PMC Article
3. CD8+ TCR Bias and Immunodominance in HIV-1 Infection.
Kløverpris HN, McGregor R, McLaren JE, Ladell K, Harndahl M, Stryhn A, Carlson JM, Koofhethile C, Gerritsen B, Keşmir C, Chen F, Riddell L, Luzzi G, Leslie A, Walker BD, Ndung'u T, Buus S, Price DA, Goulder PJ. J Immunol. 2015 Jun 1;194(11):5329-45. doi: 10.4049/jimmunol.1400854. Epub 2015 Apr 24. PMID: 25911754 Free PMC Article
4. Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load. Kløverpris HN, McGregor R, McLaren JE, Ladell K, Stryhn A, Koofhethile C, Brener J, Chen F, Riddell L, Graziano L, Klenerman P, Leslie A, Buus S, Price DA, Goulder P. AIDS. 2014 Sep 10;28(14):2007-21.
PMID: 24906112 Free PMC Article
5. Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. J Virol. 2014 May;88(9):4668-78. doi: 10.1128/JVI.03303-13. Epub 2014 Feb 5. PMID: 24501417 Free PMC Article
6. Mosaic HIV-1 Gag antigens can be processed and presented to human HIV-specific CD8+ T cells.
Ndhlovu ZM, Piechocka-Trocha A, Vine S, McMullen A, Koofhethile KC, Goulder PJ, Ndung'u T, Barouch DH, Walker BD. J Immunol. 2011 Jun 15;186(12):6914-24. doi: 10.4049/jimmunol.1004231. Epub 2011 May 16. PMID: 21576505 Free PMC Article
7. HLArestrictor--a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides. Erup Larsen M, Kloverpris H, Stryhn A, Koofhethile CK, Sims S, Ndung'u T, Goulder P, Buus S, Nielsen M.
Immunogenetics. 2011 Jan;63(1):43-55. doi: 10.1007/s00251-010-0493-5. Epub 2010 Nov 16. PMID: 21079948
8. Prevalence and potential pathogenicity of Vibrio parahaemolyticus in Chinese mitten crabs (Eriocheir sinensis) harvested from the River Thames estuary, England. Wagley S, Koofhethile K, Rangdale R. J Food Prot. 2009 Jan;72(1):60-6. PMID: 19205465
9. Comparison of V. parahaemolyticus isolated from seafoods and cases of gastrointestinal disease in the UK.
Wagley S, Koofhethile K, Wing JB, Rangdale R. Int J Environ Health Res. 2008 Aug;18(4):283-93. doi: 10.1080/09603120801911064. PMID: 18668416
HIV Research 4 Prevention conference (ORAL)
2025
Gordon Research Conference – Immunobiology/Immunochemistry (POSTER)
2025
4th Infectious Diseases in Africa Symposium (POSTER AND ORAL)
2025
SA AIDS conference (POSTER)
2025
Keystone HIV Immune Activation Conference (POSTER)
2025
UKZN- Laboratory Medicine and Medical Sciences Reserch Symposium (ORAL)
2025
Biostatistics course
2025
Gorgon Research Seminar- Immunobiology/Immunochemistry
2025
Advanced Vaccine course
2025
Flow cytometry workshop
2025
Scientific reading and writing, publishing course by OWSD
2025
AIDS Vaccine conference
2025
64th Lindau Noble laureates meeting Medicine/Physiology
2025