Full Member
Eman Nossier
Membership since:
2025
Field of activity:
About me
Eman Nossier is a Professor of Pharmaceutical Medicinal Chemistry at the Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. Nossier received her Bachelor’s degree in Pharmaceutical Sciences (2002), Master’s (2009) and Ph.D. degree (2014) in Pharmaceutical chemistry from Faculty of Pharmacy (Girls), Al-Azhar University in Cairo. She is a member in the Egyptian Chemical Society, the Arab Association of Pharmacy Progress and recently in the Egyptian National Committee of Drugs by Academy of Scientific Research and Technology (ASRT) and The Organization for Women in Science for the Developing World (OWSD), Trieste, Italy. She participated in many research projects funded by the National Research Centre, STDF, Cairo, Egypt, and Saudi Arabia. Additionally, she actively participated in numerous national and international conferences and workshops held in Saudi Arabia, India, Nigeria, and Italy. • She got The best Scientific Production at the Faculty of Pharmacy (Girls), Al-Azhar University (2021-2022), was the Winner of the ASRT and State Prizes for Individuals in the Field of Medical Sciences (Professor Dr. Shawky Al-Hadad prize for cancer tumors), 2024 and included in the Stanford University World's Top 2% Scientists List for 2024 (published in 2025).
Nossier is a section editor in Azhar International Journal of Pharmaceutical and Medical Sciences. Her research interests center on designing and synthesizing anticancer, anti-inflammatory, and antimicrobial agents using molecular modeling studies. She has authored more than 100 publications (2012-2025) with Scopus H-index 32.
Degrees:
2014
Doctorate Chemical Sciences
Pharmaceutical Medicinal Chemistry
Publications resulting from Research
• Hoda H. Fahmy, Nagy M. Khalifa, Eman S. Nossier, Mohamed M. Abdulla and Magda M. F. Ismail. Synthesis and Anti-inflammatory Evaluation of New Substituted 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-Pyrazole derivatives. Acta Poloniae Pharmaceutica Drug Research. 69 ( 3), 411-21(2012).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, and Mohamed M. Abdulla. Design, Docking, and Synthesis of Some New Pyrazoline and Pyranopyrazole Derivatives as Anti-inflammatory Agents. Latin American Journal of Pharmacy. 51, 450-8(2014).
• Eman S. Nossier, Salwa M. El-Hallouty and Eman R. Zaki. Synthesis, anticancer Evaluation and Molecular Modeling of Some Substituted Thiazolidinonyl and Thiazolyl Pyrazole Derivatives. International Journal of Pharmacy and Pharmaceutical Sciences. 7(11), 353-9 (2015).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy and Eman S. Nossier. Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities. Molecules. (21) 271 (2016).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Hend M. El-Sahrawy and Eman S. Nossier. Anticancer Activities of a Novel Series of Polysubstituted Pyrazole Derivatives linked to Nitrogenous Heterocyclic Ring Systems. Latin American Journal of Pharmacy. 35 (4), 740-8(2016).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy and Eman S. Nossier. Biological Evaluation of Novel 1,3-Diaryl-1H-Pyrazoles Incorporating Different Heterocyclic Ring Systems as Potent Cytotoxic Agents. Latin American Journal of Pharmacy. 35 (6), 1340-7(2016).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy, Eman S. Nossier, and Mamdouh M. Ali. In vivo Cytotoxicity of Polysubstituted Pyrazole Derivatives against Liver Cancer Cell Line. Latin American Journal of Pharmacy. 35(8), 1783-90 (2016).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Hend M. El-Sahrawy and Eman S. Nossier. Anticancer evaluation of novel 1,3,4-trisubstituted pyrazole candidates bearing different nitrogenous heterocyclic Moieties. Biomedical Research 27 (4): 1087-1093 (2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis and Characterization of Novel 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) and Dihydro-alkylthio-benzyloxopyrimidine (S-DABO) Analogs Containing a Benzo[d]thiazol Moiety. Russian Journal of General Chemistry. 86 (2), 400-405(2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis of Some Novel S-Alkylated and S-Glycosylated Hydantoin Derivatives Containing Pyrene Moiety. Russian Journal of General Chemistry. 86 (4), 919-923(2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis, Reactions, and Antimicrobial Activity of Some Novel Fused Thiazolo[3,2-a]pyrimidine-5H-indeno[1,2-d]pyrimidine Derivatives. Russian Journal of General Chemistry. 86 (8), 1948-1953(2016).
• N. M. Khalifa, A. E. G. Amr, M. A. Al-Omar and E. S. Nossier. Synthesis, Characterization, and Antimicrobial Activity of Some Chiral Linear Carboxamides with Incorporated Peptide Linkage. Russian Journal of General Chemistry. 86 (12), 2785-2790(2016).
• E. M. M. El-Deen, N. A. Mohamed, W. S. El-Serwy, T. M. Abdelghany and E. S. Nossier, Synthesis, Molecular Docking and Cytotoxicity Evaluation of Novel 1,2- Disubstituted Benzimidazole Derivatives Against Liver and Breast Cancer Cell Lines. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 7 (5), 1599-1615 (2016).
• Walaa S. El-serwy, Neama A. Mohamed, Weam S. El-serwy, Eman S. Nossier and Khaled Mahmoud. Synthesis, Molecular Modeling Studies And Biological Evaluation Of Novel Pyrazole As Antitumor And EGFR Inhibitors. International Journal of Pharmacy & Technology. 8(4), 25192-25209(2016).
• Eman S. Nossier, Hoda H. Fahmy, Nagy M. Khalifa, Wafaa I. El-Eraky and Marawan A. Baset , Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents. Molecules. 22, 512(2017).
• Nagy M. KHALIFA, Mohamed A. AL-OMAR, Eman S. NOSSIER & Hassan Z. GHANEM, Anti-inflammatory Activity of Some Newly 8-Hydroxy-7-iodo-5-sulfonamide Quinolines Linked Different Heterocyclic Ring Systems. Latin American Journal of Pharmacy. 36 (3), 486-494 (2017).
• Nagy M. KHALIFA, Mohamed A. AL-OMAR, Eman S. NOSSIER & Hassan Z. GHANEM, Antioxidant Activity of Some Newly Synthesized Substituted Pyrenyl Pyridine Derivatives. Latin American Journal of Pharmacy. 36 (3), 535-40 (2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis and Characterization of Some Novel 1,3-Diaryl Pyrazole Bearing 2-Oxopyridine-3,5-dicarbonitrile Derivatives. Russian Journal of General Chemistry. 87 (4), 846-849(2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis of Some New Pyrazolyl-Thiazolidinone Derivatives Starting from 1-(3-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carboxaldehyde. Russian Journal of General Chemistry. 87 (4), 868-872(2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis and Characterization of New Pyrazolyl-Substituted Thiazolidinone, Thiazole, and Thiazoline Candidates. Russian Journal of General Chemistry. 87 (6), 1295-1299(2017).
• N. M. Khalifa, M. A. Al-Omar and E. S. Nossier. Synthesis and some reactions of novel (4Z)-4-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-hydrazinyl-1-phenyl-1H-imidazol-5(4H)-ones. Russian Journal of General Chemistry. 87 (7), 1621-1626(2017).
• N. M. Khalifa, M. A. Al-Omar and E. S. Nossier. Biological Evaluation of Newly Synthesized Quinazolinyl-Chalcone Derivatives. Journal of Computational and Theoretical Nanoscience. 14 (8), 3821-3826(2017).
• Heba S. A. Elzahabi, Eman S. Nossier, Nagy M. Khalifa, Rania A. Alasfoury and May A. El-Manawaty. Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry. 33( 1), 546–557(2018).
• N. M. Khalifa, E. S. Nossier and A. E. Amr. "Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates". Russian Journal of General Chemistry. 88 (6), 1228-1231(2018).
• Abd El-Galil E. Amr, Mohamed H. Abo-Ghalia, Gaber O. Moustafa, Mohamed A. Al-Omar, Eman S. Nossier and Elsayed A. Elsayed. "Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors". Molecules. 23, 2416(2018).
• Eman S. Nossier, Somaia S. Abd El-Karim, Nagy M. Khalifa, Ali S. El-Sayed, Emad S. I. Hassan and Salwa M. El-Hallouty. "Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives". Molecules. 23, 3074(2018).
• N. M. Khalifa, A. S. El-Sayed, S. S. Abd El-Karim, E. S. Hassan, E. S. Nossier, and A. G. Shalaby. "1,3,4-Triarylpyrazoles Containing 2-Thioxoimidazolidinones and Different Fused Systems: Synthesis and Antimicrobial Activity". Russian Journal of General Chemistry. 88 (12), 2646-2652(2018).
• Abd El-Galil E. Amr, Elsayed A. Elsayed, Mohamed A. Al-Omar, Hanan O. Badr Eldin, Eman S. Nossier and Mohamed M. Abdallah. "Design, Synthesis, Anticancer Evaluation and Molecular Modeling of Novel Estrogen Derivatives". Molecules. 24, 416(2019).
• Ibrahim F. Zeid, Neama A. Mohamed, Nagy M. Khalifa, Emad M. Kassem, Eman S. Nossier, Ahmed A. Salman, Khaled Mahmoud and Mohamed A. Al-Omar. "PI3K Inhibitors of Novel Hydrazide Analogues Linked 2-Pyridinyl Quinazolone Scaffold as Anticancer Agents". Journal of Chemistry. (2019), https://doi.org/10.1155/2019/6321573.
• Mohamed El-Naggar, Hanan A. Sallam, Safaa S. Shaban, Salwa S. Abdel-Wahab, Abd El-Galil E. Amr, Mohammad E. Azab, Eman S. Nossier and Mohamed A. Al-Omar. "Design, Synthesis, and Molecular Docking Study of Novel Heterocycles Incorporating 1,3,4-Thiadiazole Moiety as Potential Antimicrobial and Anticancer Agents". Molecules. 24, 1066(2019).
• Walaa S. El-serwy, Hanaa S. Mohamed, Weam S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Eman S. Nossier and Al Shimaa G. Shalaby. "Molecular Docking Study of Newly Synthesized Thiopyrimidines as Antimicrobial Agents Targeting DNA Gyrase Enzyme". Journal of Heterocyclic Chemistry. 56, 2027(2019).
• Asmaa F. Kassem, Gaber O. Moustafa, Eman S. Nossier, Hemat S. Khalaf, Marwa M. Mounier, Suliman A. Al-Yousef and Sabry Y. Mahmoud. " In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl)isophthalamide". Journal of Enzyme Inhibition and Medicinal Chemistry. 34( 1), 1247–1258(2019).
• Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Mohamed El-Naggar, Eman S. Nossier and Abd El-Galil E. Amr. "Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies". Journal of Enzyme Inhibition and Medicinal Chemistry. 34( 1), 1259–1270(2019).
• Ashraf S. Hassan, Ahmed A. Askar, Eman S. Nossier, Ahmed M. Naglah, Gaber O. Moustafa and Mohamed A. Al-Omar. "Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles". Molecules. 24, 3130 (2019).
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Sherifa Hasabelnaby, Eman A. Karam and Eman S. Nossier. "Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine-Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors". Molecules. 24, 3650 (2019).
• Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, Abd El-Galil E. Amr and Rashed N. Herqash. "Novel Synthesis of Pyrazole-Containing Thiophene, 2-Alkyloxypyridine and Thieno[2,3-d]Pyrimidine Scaffolds as Analgesic Agents". Bull. Chem. Soc. Ethiop. 2019, 33(3), 505-515.
• Magda M.F. Ismail, Hanan Gaber Abdulwahab, Eman Samir Nossier, Nagwan Galal El Menofy, Basma Abdelhameed Abdelkhalek. "Synthesis of Novel 2-Aminobenzothiazole Derivatives as Potential Antimicrobial Agents with Dual DNA Gyrase/Topoisomerase IV Inhibition". Bioorganic Chemistry 94, 103437 (2020).
• Abd El-Galil E. Amr, Randa E. Abdel Mageid, Mohamed El-Naggar, Ahmed M. Naglah, Eman S. Nossier, and Elsayed A. Elsayed. "Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl)Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A". Molecules 2020, 25, 1096.
• Dina H. Dawood, Eman S. Nossier, Mamdouh M. Ali, and Abeer E. Mahmoud. "Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase". Bioorganic Chemistry 2020,101, 103916.
• Heba E. Hashem, Abd El-Galil E. Amr, Eman S. Nossier, Elsayed A. Elsayed, Eman M. Azmy. "Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors". Molecules. 2020; 25(12):2766.
• H.S. Abd-Elghaffar, M.A. El-Hashash, S.F. Mohamed, A.A. Ibrahim, A.E. Amr, M.A. Al-Omar, E.S. Nossier. "Synthesis and Anti-Proliferative Activity of Novel Tricyclic Compounds Derived from 2-Substituted 1, 3-Indandione". Russian Journal of General Chemistry. 2020, 90(4):686-96.
• Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Abd El-Galil E. Amr, Mohamed A. Al-Omar, Eman S. Nossier, Elsayed A. Elsayed. "Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and in silico studies". Journal of Enzyme Inhibition and Medicinal Chemistry. 35( 1), 1491–1502(2020).
• Walaa S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Eman S. Nossier, Al Shimaa G. Shalaby. "Novel 5-Nitro Isatin derivatives as DNA Gyrase inhibitors: synthesis, antimicrobial evaluation, molecular docking, ADMET predictions and QSAR studies". Chem. Biol. Lett. 2020, 7(4), 197‐206.
• Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, Mohamed A. Al-Omar, and Abd El-Galil E. Amr. "New Polysubstituted Pyrazole Derivatives: Synthesis and Cytotoxicity Studies". Russian Journal of General Chemistry 90(6), 1062–1068(2020).
• Fatma H. Mohamed, Ahmad M. Shalaby, Hanan A. Soliman, Ahmed Z. Abdelazem, Marwa M. Mounier, Eman S. Nossier, Gaber O. Moustafa. "Design, Synthesis and Molecular Docking Studies of Novel Cyclic Pentapeptides Based on Phthaloyl Chloride with Expected Anticancer Activity". Egypt.J.Chem. 63(5), 1723 - 1736(2020).
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Eman A. Karam, Eman S. Nossier and Marwa F. Ahmed. "Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors". Antibiotics 9, 695(2020).
• Walaa S. El-serwy, Hanaa S. Mohamed, Weam S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Khaled Mahmoud and Eman S. Nossier. "Thiopyrimidine-5-carbonitrile Derivatives as VEGFR-2 Inhibitors: Synthesis, Anticancer Evaluation, Molecular Docking, ADME Predictions and QSAR Studies". ChemistrySelect 5, 15243– 15253 (2020).
• Reham R. Khattab, Asma K. Alshamari, Allam A. Hassan, Hussein H. Elganzory, Wael A. El-Sayed, Hanem M. Awad, Eman S. Nossier & Nasser A. Hassan. "Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazolethienopyrimidine hybrid glycosides targeting EGFR". Journal of Enzyme Inhibition and Medicinal Chemistry, 36 (1), 504–516 (2021).
• Somaia S. Abd El-Karim, Hanaa S. Mohamed, Mohamed F. Abdelhameed, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Eman S. Nossier. "Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity". Bioorganic Chemistry, 111, 104827 (2021).
• Eman A. Abd El-Meguid, Gaber O. Moustafa, Hanem M. Awad, Eman R. Zaki, and Eman S. Nossier. "Novel Benzothiazole Hybrids Targeting EGFR: Design, Synthesis, Biological Evaluation and Molecular Docking Studies". Journal of Molecular Structure, 130595(2021).
• Ashraf S. Hassan, Gaber O. Moustafa, Hanem M. Awad, Eman S. Nossier and Mohamed F. Mady. "Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids." ACS Omega 6, 12361−12374 (2021).
• Eman A. Fayed, Eman S. Nossier, Ahmed Atef, and Samar A. El-Kalyoubi. "In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors." Molecular Diversity 1-23 (2021).
• Ismail M.M. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Mohamed A. M. Gad-Elkareem, Manal M. Anwar, Eman S. Nossier. "New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies" Bioorganic Chemistry, 114, 105078 (2021).
• Israa A. Seliem, Siva S. Panda, Adel S. Girgis, Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, Eman S. Nossier, Fatma Rasslan, Aladdin M. Srour, Rajeev Sakhuja, Tarek S. Ibrahim, Zakaria K.M. Abdel-samii, Amany M.M. Al-Mahmoudy. "New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2" Bioorganic Chemistry, 114, 105117 (2021).
• Gaber O. Moustafa, Ahmed Shalaby, Ahmed M. Naglah, Marwa M. Mounier, Heba El-Sayed, Manal M. Anwar, and Eman S. Nossier. "Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives" Molecules 26(15), 4573 (2021).
• Reham R. Khattab, Allam A. Hassan, Dalia A. A. Osman, Farouk M. Abdel-Megeid, Hanem M. Awad, Eman S. Nossier, and Wael A. El-Sayed. "Synthesis, anticancer activity and molecular docking of new triazolo [4,5-d] pyrimidines based thienopyrimidine system and their derived N-glycosides and thioglycosides." Nucleosides, Nucleotides & Nucleic Acids, 1-24 (2021).
• Amira A. El-Sayed, Eman S. Nossier, Abdulrahman A. Almehizia, and Abd El-Galil E. Amr. "Design, synthesis, anticancer evaluation and molecular docking study of novel 2,4-dichlorophenoxymethyl-based derivatives linked to nitrogenous heterocyclic ring systems as potential CDK-2 inhibitors." Journal of Molecular Structure, 1247, 131285 (2022).
• Mohamed A. Hawata, Wael A. El-Sayed, Eman S. Nossier, and Adel A-H. Abdel-Rahman."Synthesis and Cytotoxic Activity of New Pyrimido [1, 2-c] quinazolines,[1, 2, 4] triazolo [4, 3-c] quinazolines and (quinazolin-4-yl)-1H-pyrazoles Hybrids." Biointerface Research in Applied Chemistry, 12(4), 5217–5233 (2022).
• Ismail M. M. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Mohamed A. M. Gad-Elkareem, Somaia S. Abd El-Karim and Eman S. Nossier, Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi-targeting kinase inhibitors. RSC Advances, 12, 561–577 (2022).
• Eman A. Abd El-Meguid, Eman M. Mohi El-Deen, Gaber O. Moustafa, Hanem M. Awad, and Eman S. Nossier. "Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1." Bioorganic Chemistry 105504, (2022).
• Heba S. A. El‐Zahabi, Eman S. Nossier, Safya M. Mousa, Heba Hassan, AL Shimaa G. Shalaby, and Reem K. Arafa. "Antibacterial and anticancer profiling of new benzocaine derivatives: Design, synthesis, and molecular mechanism of action." Archiv der Pharmazie e2100451(2022).
• Riham M. Bokhtia, Adel S. Girgis, Tarek S. Ibrahim, Fatma Rasslan, Eman S. Nossier, Reham F. Barghash, Rajeev Sakhuja, Eatedal H. Abdel-Aal, Siva S. Panda, and Amany MM Al-Mahmoudy. "Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates." Pharmaceuticals 15(2), 191 (2022).
• Mai E. Hussein, Osama G. Mohamed, Ahlam M. El Fishawy, Hesham I. El-Askary, Amira S. El Senousy, Ahmed A. El-Beih, Eman S. Nossier, Ahmed M. Naglah, Abdulrahman A. Almehizia, Ashootosh Tripathi and Ahmed A. Hamed. "Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques". Molecules 27(3), 1117 (2022).
• Heba E. Hashem, Abd El-Galil E. Amr, Eman S. Nossier, Manal M. Anwar, and Eman M. Azmy. "New Benzimidazole-, 1, 2, 4-Triazole-, and 1, 3, 5-Triazine-Based Derivatives as Potential EGFRWT and EGFRT790M Inhibitors: Microwave-Assisted Synthesis, Anticancer Evaluation, and Molecular Docking Study." ACS omega 7, 7155−7171 (2022).
• Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh and Asmaa F. Kassem. Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2. Molecules 27, 2047 (2022).
• Dina H. Dawood, Eman S. Nossier, Mohamed F. Abdelhameed, Gihan F. Asaad, and Sahar S. Abd El-Rahman. "Design, synthesis, anti-inflammatory evaluation and molecular docking of novel thiophen-2-ylmethylene-based derivatives as potential TNF-α production inhibitors." Bioorganic Chemistry 105726 (2022).
• Zahra M.Alamshany, Nada Y. Tashkandi, Ismail MM Othman, Manal M. Anwar, and Eman S. Nossier. "New thiophene, thienopyridine and thiazoline-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents and multitargeting kinase inhibitors." Bioorganic Chemistry 105964(2022).
• Heba SA Elzahabi, Eman S. Nossier, Rania A. Alasfoury, May El-Manawaty, Sara M. Sayed, Eslam B. Elkaeed, Ahmed M. Metwaly, Mohamed Hagras, and Ibrahim H. Eissa. "Design, synthesis, and anti-cancer evaluation of new pyrido [2, 3-d] pyrimidin-4 (3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers." Journal of Enzyme Inhibition and Medicinal Chemistry 37, no. 1, 1053-1076 (2022).
• Ismail MM. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Eman S. Nossier, Manal M. Anwar, and Hyam A. Radwan. "Chemical synthesis and molecular docking study of new thiazole, thiophene, and thieno[2,3-d]pyrimidine derivatives as potential antiproliferative and antimicrobial agents." Journal of Molecular Structure 133926 (2022).
• Eman S. Nossier, Rania A. Alasfoury, Mohamed Hagras, May El-Manawaty, Sara M. Sayed, Ibrahim M. Ibrahim, Hazem Elkady, Ibrahim H. Eissa, and Heba SA Elzahabi. "Modified pyrido [2, 3-d] pyrimidin-4 (3H)-one derivatives as EGFRWT and EGFRT790M inhibitors: Design, synthesis, and anti-cancer evaluation." Journal of Molecular Structure 133971(2022).
• Eman M. Mohi El‐Deen, Eman S. Nossier and Eman A. Karam. "New Quinazolin‐4(3H)‐one Derivatives Incorporating Hydrazone and Pyrazole Scaffolds as Antimicrobial Agents Targeting DNA Gyraze Enzyme" Scientia Pharmaceutica 90, 52 (2022).
• Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, and Asmaa F Kassem. "New 1, 2, 3-Triazole-Coumarin-Glycoside Hybrids and Their 1, 2, 4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation." Molecules 27(17) 5688 (2022).
• Hussein H. Elganzory, Fahad M. Alminderej, Mohamed N. El-Bayaa, Hanem M. Awad, Eman S. Nossier, and Wael A. El-Sayed. "Design, Synthesis, Anticancer Activity and Molecular Docking of New 1, 2, 3-Triazole-Based Glycosides Bearing 1, 3, 4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds." Molecules 27 (20) 6960 (2022).
• Aladdin M. Srour, Dina H. Dawood, Eman S. Nossier, Riham A. El-Shiekh, Abeer E. Mahmoud, Amal G. Hussien, Mervat M. Omran, and Mamdouh M. Ali. "Design, Synthesis and Molecular Docking Simulation of Oxindole-Based Derivatives with Dual VEGFR-2 and Cholinesterase Inhibitory Activities." Journal of Molecular Structure 1271, 134130 (2023).
• Rania A. Alasfoury, Eman S. Nossier, May El-Manawaty, and Heba SA Elzahabi. "Novel Pyrido-Thiazolo-Pyrimidinone Hybrids targeting EGFRWT and EGFRT790M: Design, Synthesis, Anticancer Activity and docking simulation." Azhar International Journal of Pharmaceutical and Medical Sciences 3(1) 112-119 (2023).
• Zahra M. Alamshany, Eman M. Algamdi, Ismail M. M. Othman, Manal M. Anwar and Eman S. Nossier "New pyrazolopyridine and pyrazolothiazole-based compounds as anti-proliferative agents targeting c-Met kinase inhibition: design, synthesis, biological evaluation, and computational studies" RSC Advances 13, 12889–12905 (2023).
• Asmaa F. Kassem, Mohamed A. Omar, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Novel Pyridine-Thiazolidinone-Triazole Hybrid Glycosides Targeting EGFR and CDK-2: Design, Synthesis, Anticancer Evaluation, and Molecular Docking Simulation." Journal of Molecular Structure 1294, 136358 (2023).
• Dina H. Dawood, Manal M. Sayed, Sally TK Tohamy, and Eman S. Nossier. "New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies." ACS Omega 8, 39250−39268 (2023).
• Heba E. Hashem, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Ahmed M. Naglah, Benson M. Kariuki, Heba A. Eassa and Eman S. Nossier. "Nanoparticles of a Pyrazolo-Pyridazine Derivative as Potential EGFR and CDK-2 Inhibitors: Design, Structure Determination, Anticancer Evaluation and In Silico Studies." Molecules 28, 7252 (2023).
• Dina H. Dawood, Dalia O. Saleh, Gehad A. Abdel Jaleel and Eman S. Nossier. " New Chromone-Thiazolopyrimidine Hybrids as Potent TNF-α, IL-6 and PGE2 Inhibitors: Synthesis, Anti-Inflammatory Evaluation and Molecular Modeling Studies." Polycyclic Aromatic Compounds 44(10), 6564–6588 (2024).
• Nossier, E.S., Khalifa, N.M., Fahmy, H.H., Ismail, M.M.F., El-Sahrawy, H.M. and Ali, M.M.,. Novel Bipyrazole Targeting Dual CDK-2 and VEGFR-2 Kinases: Synthesis, Anticancer Evaluation, and In Silico Studies. Russian Journal of Bioorganic Chemistry, 50(1), 227-238 (2024).
• Rasha Z. Batran, , Eman Y. Ahmed, Eman S. Nossier, Hanem M. Awad, and Nehad A. Abdel Latif. "Anticancer activity of new triazolopyrimidine linked coumarin and quinolone hybrids: synthesis, molecular modeling, TrkA, PI3K/AKT and EGFR inhibition." Journal of Molecular Structure 137790 (2024).
• Fatma H Mohamed, Gaber O Moustafa, Eman Nossier, and Marwa Mounier. "In Vitro Anticancer Potentiality and Molecular Modelling Study of Novel Cyclic Pentapeptides based on 1,2-benzenedicarbonyl chloride." Egyptian Journal of Chemistry 67, no. 13 (2024): 567-576.
• Fatma H Mohamed, Gaber O Moustafa, Eman Nossier, and Marwa Mounier. "Design, Synthesis and Molecular Docking Studies of Novel Amino Acids and Peptide Derivatives Based on Phthaloyl Chloride With Expected Anticancer Activity." Egyptian Journal of Chemistry 67, no. 13 (2024): 577-587.
• Eman S. M. Elsenbawy, Zafer S. Alshehri, Nouf A. Babteen, Adel A.-H. Abdel-Rahman, Mai A. El-Manawaty, Eman S. Nossier, Reem K. Arafa and Nasser A. Hassan "Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidine Derivatives." Molecules 29, 1067 (2024).
• Asmaa F. Kassem, Ahmed Younis, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Pyridine-Based Glycosides Bearing 1, 2, 4-Triazole and Their 1, 3, 4-oxadiazole analogues as Potential EGFR and CDK-2 Inhibitors: Design, Synthesis, Antiproliferative Activity and In Silico Studies." Journal of Molecular Structure 138741(2024).
• Yasmin S. Sheta, Marwa T. Sarg, Fatma G. Abdulrahman, Eman S. Nossier, and Ebtehal M. Husseiny. "Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights." Bioorganic Chemistry 107471(2024).
• Dina Dawood, Nesma Abo El-Nasr, Passant Mustafa, Dalia Saleh, Omar Farid, and Eman Nossier. "Synthesis and molecular modeling study of new pyrimidine-based derivatives as anticonvulsant agents." Egyptian Journal of Chemistry (2024).
• Hebat-Allah S. Abbas, Eman S. Nossier, May A. El-Manawaty, and Mohamed N. El-Bayaa. "New sulfonamide-based glycosides incorporated 1, 2, 3-triazole as cytotoxic agents through VEGFR-2 and carbonic anhydrase inhibitory activity." Scientific reports 14, no. 1, 13028 (2024).
• Zahra M. Alamshany1, Eman S. Nossier. “New thiazole Derivatives Linked to Pyridine, Fused Pyridine, Pyrimidine and Thiazolopyrimidine Scaffolds with Potential dual Anticancer and Antimicrobial Activities: Design, Synthesis and Docking Simulation” Journal of Molecular Structure 138973 (2024).
• Gaber O. Moustafa, , Atef Kalmouch, Somaia S. Abd El-Karim, Eman S. Nossier, Marwa M. Mounier, Heba El-Sayed, Abdulrahman A. Almehizia, Ahmed M. Naglah, and Amer A. Zen. "Target-based anticancer glycyrrhetinic derivatives: Design, synthesis, biological assessment and molecular docking studies." Bulletin of the Chemical Society of Ethiopia 38, no. 5, 1369-1392 (2024).
• Dania Alweet, Mohamed El-Bayaa, Sobhi Gomha, Fahad Alminderej, Eman S. Nossier, Wael A El-Sayed, and Ahd Alenazy. "Synthesis, Molecular Docking and Anticancer Activity of New Pyridyl-1, 2, 4-Triazole-Thioglycosides and Their Pyridyl-[1, 2, 4] triazolo [1, 5-a] pyridine-Glycoside Analogues." Egyptian Journal of Chemistry (2024).
• Adel A-H. Abdel-Rahman, Mohamed N. El-Bayaa, Asmaa Sobhy, Eman M. El-Ganzoury, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Novel quinazolin-4-one based derivatives bearing 1, 2, 3-triazole and glycoside moieties as potential cytotoxic agents through dual EGFR and VEGFR-2 inhibitory activity." Scientific Reports 14, no. 1, 24980 (2024).
• Aladdin M. Srour, Eman S. Nossier, Najla A. Altwaijry, Safeya M. Mousa, Hanem M. Awad, and Heba SA Elzahabi. "New pyrano-pyridine conjugates as potential anticancer agents: design, synthesis and computational studies." Future Medicinal Chemistry 16, 2567–2582 (2024).
• Nadia M. Hamdy, Emad B. Basalious, Mona G. El-Sisi, Maha Nasr, Ahmed M. Kabel, Eman S. Nossier, and Ashraf H. Abadi. "Advancements in current one-size-fits-all therapies compared to future treatment innovations for better improved chemotherapeutic outcomes: a step-toward personalized medicine." Current Medical Research and Opinion 1-34, (2024).
• Aisha A. Alsfouk, , Ismail MM Othman, Manal M. Anwar, Walaa A. Alshareef, Asmaa Saleh, and Eman S. Nossier. "Synthesis and computational studies of new pyridine, pyrazole, pyran, and pyranopyrimidine-based derivatives of potential antimicrobial activity as DNA gyrase and topoisomerase IV inhibitors." Journal of Molecular Structure 1319, 139528 (2025).
• Wael A. El-Sayed, Mohammed SM Aladl, Eman Nossier, and Alaa MM Younis. "Chemistry of Persistent Organic Pollutants (POPs): Distribution, Environmental Impact and Mitigation Approaches." Egyptian Journal of Chemistry 68 (9), 663-677 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Manal M. Anwar, Asmaa Saleh, and Eman S. Nossier. "Design, synthesis, and in silico studies of new quinazolinones tagged thiophene, thienopyrimidine, and thienopyridine scaffolds as antiproliferative agents with potential p38α MAPK kinase inhibitory effects." RSC advances 15, no. 2 (2025): 1407-1424.
• Dina Dawood, Dalia Saleh, Nesma Abo El-Nasr, Passant Mustafa, Omar Farid, and Eman Nossier. "Synthesis and molecular modeling study of new pyrimidine-based derivatives as anticonvulsant agents." Egyptian Journal of Chemistry 68, no. 1 (2025): 109-122.
• Hagar S. El-Hema, Sara M. Soliman, Wagdy El-Dougdoug, Mohamed HM Ahmed, Abdelmotaal Abdelmajeid, Eman S. Nossier, Modather F. Hussein et al. "Design, Characterization, Antimicrobial Activity, and In Silico Studies of Theinothiazoloquinazoline Derivatives Bearing Thiazinone, Tetrazole, and Triazole Moieties." ACS Omega 10, 9703−9717 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Manal M. Anwar, Asmaa Saleh, Nada Y. Tashkandi, and Eman S. Nossier. "New quinazolinone-based heterocyclic compounds as promising antimicrobial agents: development, DNA gyrase B/topoisomerase IV inhibition activity, and in silico computational studies." Journal of Molecular Structure 1344,142953 (2025).
• Safeya M. Mousa, Eman S. Nossier, Aladdin M. Srour, Hanem M. Awad, and Heba SA Elzahabi. "Design, Synthesis, Cytotoxicity, and Docking Study of New Pyrano [3, 2–c] Pyridine-Based Derivatives." Azhar International Journal of Pharmaceutical and Medical Sciences 5, no. 2 57-65 (2025).
• Ahmad E. Mohamed, Walid E. Elgammal, Ahmed G. Ibrahim, Hamdy M. Dawaba, Eman S. Nossier, and Aya M. Dawaba. "Thiadiazole chitosan conjugates as a novel cosmetic ingredient for rinse-off hair conditioners: design, formulation, characterization and in silico-molecular docking studies." BMC Chemistry 19, 104 (2025).
• Eman S. Nossier, Manal M. Anwar, and Mohamed Ayman El-Zahabi. "Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches." Molecular Diversity 1-28 (2025).
• Ahmed M. Hussein, Walaa I. EL‐Sofany, Fahad M. Alminderej, Abuzar EAE Albadri, Hanem M. Awad, Eman S. Nossier, and Wael A. El‐Sayed. "New Thiadiazole‐Triazole Hybrid Glycosides as Potential EGFR and VEGFR‐2 Inhibitors: Synthesis, Anticancer Activity, and Docking Simulation." ChemistrySelect 10, no. 28, e04887 (2025).
• Sara M. Soliman, Adel A.-H. Abdel-Rahman, Eman S. Nossier, Modather F. Hussein, Amr Sabry & Hagar S. El-Hema. "Design, antiproliferative potency, and in silico studies of novel 5-methylfuran-3-yl)thio)-3- phenylquinazolin-4(3H)-one based derivatives as potential EGFR inhibitors" Scientific Reports 15, 27992 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Hamdi MD Nasr, Esam A. Ishak, Asmaa Saleh, and Eman S. Nossier. "Synthesis, Characterization, Computational Studies and In Vitro Biological Effects of Novel Pyrazoles, Pyridazines, Thiazoles Containing a Quinazoline Scaffold." ChemistrySelect 10( 30), e01583 (2025).
• Hagar S. El-Hema, Mohamed F. Mady, Adel A.-H. Abdel-Rahman, Eman S. Nossier, Ahmed F. El-Sayed, Amr Sabry, Murad El-Feky, Mohamed A. Hawata. “Novel pyrimidopyridothiazine based derivatives as potential anticancer and antibacterial agents: A step towards design and synthesis of multi-targeted therapeutics” Journal of Molecular Structure1349, 143790 (2026).
• Manar M. Saber, Reham R. Khattab, Sherin H. Pasha, Moshira M. Abd-El Wahed, Ahmed A. El-Sayed, Adel AH Abdel-Rahman, Eman S. Nossier, and Nasser A. Hassan. "Novel Glycosylated Dihydropyridine-Based Nanoformulations as EGFR Inhibitors." Egyptian Journal of Chemistry (2025).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, and Mohamed M. Abdulla. Design, Docking, and Synthesis of Some New Pyrazoline and Pyranopyrazole Derivatives as Anti-inflammatory Agents. Latin American Journal of Pharmacy. 51, 450-8(2014).
• Eman S. Nossier, Salwa M. El-Hallouty and Eman R. Zaki. Synthesis, anticancer Evaluation and Molecular Modeling of Some Substituted Thiazolidinonyl and Thiazolyl Pyrazole Derivatives. International Journal of Pharmacy and Pharmaceutical Sciences. 7(11), 353-9 (2015).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy and Eman S. Nossier. Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities. Molecules. (21) 271 (2016).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Hend M. El-Sahrawy and Eman S. Nossier. Anticancer Activities of a Novel Series of Polysubstituted Pyrazole Derivatives linked to Nitrogenous Heterocyclic Ring Systems. Latin American Journal of Pharmacy. 35 (4), 740-8(2016).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy and Eman S. Nossier. Biological Evaluation of Novel 1,3-Diaryl-1H-Pyrazoles Incorporating Different Heterocyclic Ring Systems as Potent Cytotoxic Agents. Latin American Journal of Pharmacy. 35 (6), 1340-7(2016).
• Hoda H. Fahmy, Nagy M. Khalifa, Magda M. F. Ismail, Hend M. El-Sahrawy, Eman S. Nossier, and Mamdouh M. Ali. In vivo Cytotoxicity of Polysubstituted Pyrazole Derivatives against Liver Cancer Cell Line. Latin American Journal of Pharmacy. 35(8), 1783-90 (2016).
• Magda M. F. Ismail, Nagy M. Khalifa, Hoda H. Fahmy, Hend M. El-Sahrawy and Eman S. Nossier. Anticancer evaluation of novel 1,3,4-trisubstituted pyrazole candidates bearing different nitrogenous heterocyclic Moieties. Biomedical Research 27 (4): 1087-1093 (2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis and Characterization of Novel 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) and Dihydro-alkylthio-benzyloxopyrimidine (S-DABO) Analogs Containing a Benzo[d]thiazol Moiety. Russian Journal of General Chemistry. 86 (2), 400-405(2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis of Some Novel S-Alkylated and S-Glycosylated Hydantoin Derivatives Containing Pyrene Moiety. Russian Journal of General Chemistry. 86 (4), 919-923(2016).
• N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr. Synthesis, Reactions, and Antimicrobial Activity of Some Novel Fused Thiazolo[3,2-a]pyrimidine-5H-indeno[1,2-d]pyrimidine Derivatives. Russian Journal of General Chemistry. 86 (8), 1948-1953(2016).
• N. M. Khalifa, A. E. G. Amr, M. A. Al-Omar and E. S. Nossier. Synthesis, Characterization, and Antimicrobial Activity of Some Chiral Linear Carboxamides with Incorporated Peptide Linkage. Russian Journal of General Chemistry. 86 (12), 2785-2790(2016).
• E. M. M. El-Deen, N. A. Mohamed, W. S. El-Serwy, T. M. Abdelghany and E. S. Nossier, Synthesis, Molecular Docking and Cytotoxicity Evaluation of Novel 1,2- Disubstituted Benzimidazole Derivatives Against Liver and Breast Cancer Cell Lines. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 7 (5), 1599-1615 (2016).
• Walaa S. El-serwy, Neama A. Mohamed, Weam S. El-serwy, Eman S. Nossier and Khaled Mahmoud. Synthesis, Molecular Modeling Studies And Biological Evaluation Of Novel Pyrazole As Antitumor And EGFR Inhibitors. International Journal of Pharmacy & Technology. 8(4), 25192-25209(2016).
• Eman S. Nossier, Hoda H. Fahmy, Nagy M. Khalifa, Wafaa I. El-Eraky and Marawan A. Baset , Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents. Molecules. 22, 512(2017).
• Nagy M. KHALIFA, Mohamed A. AL-OMAR, Eman S. NOSSIER & Hassan Z. GHANEM, Anti-inflammatory Activity of Some Newly 8-Hydroxy-7-iodo-5-sulfonamide Quinolines Linked Different Heterocyclic Ring Systems. Latin American Journal of Pharmacy. 36 (3), 486-494 (2017).
• Nagy M. KHALIFA, Mohamed A. AL-OMAR, Eman S. NOSSIER & Hassan Z. GHANEM, Antioxidant Activity of Some Newly Synthesized Substituted Pyrenyl Pyridine Derivatives. Latin American Journal of Pharmacy. 36 (3), 535-40 (2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis and Characterization of Some Novel 1,3-Diaryl Pyrazole Bearing 2-Oxopyridine-3,5-dicarbonitrile Derivatives. Russian Journal of General Chemistry. 87 (4), 846-849(2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis of Some New Pyrazolyl-Thiazolidinone Derivatives Starting from 1-(3-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carboxaldehyde. Russian Journal of General Chemistry. 87 (4), 868-872(2017).
• N. M. Khalifa, E. S. Nossier and M. A. Al-Omar. Synthesis and Characterization of New Pyrazolyl-Substituted Thiazolidinone, Thiazole, and Thiazoline Candidates. Russian Journal of General Chemistry. 87 (6), 1295-1299(2017).
• N. M. Khalifa, M. A. Al-Omar and E. S. Nossier. Synthesis and some reactions of novel (4Z)-4-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-hydrazinyl-1-phenyl-1H-imidazol-5(4H)-ones. Russian Journal of General Chemistry. 87 (7), 1621-1626(2017).
• N. M. Khalifa, M. A. Al-Omar and E. S. Nossier. Biological Evaluation of Newly Synthesized Quinazolinyl-Chalcone Derivatives. Journal of Computational and Theoretical Nanoscience. 14 (8), 3821-3826(2017).
• Heba S. A. Elzahabi, Eman S. Nossier, Nagy M. Khalifa, Rania A. Alasfoury and May A. El-Manawaty. Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry. 33( 1), 546–557(2018).
• N. M. Khalifa, E. S. Nossier and A. E. Amr. "Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates". Russian Journal of General Chemistry. 88 (6), 1228-1231(2018).
• Abd El-Galil E. Amr, Mohamed H. Abo-Ghalia, Gaber O. Moustafa, Mohamed A. Al-Omar, Eman S. Nossier and Elsayed A. Elsayed. "Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors". Molecules. 23, 2416(2018).
• Eman S. Nossier, Somaia S. Abd El-Karim, Nagy M. Khalifa, Ali S. El-Sayed, Emad S. I. Hassan and Salwa M. El-Hallouty. "Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives". Molecules. 23, 3074(2018).
• N. M. Khalifa, A. S. El-Sayed, S. S. Abd El-Karim, E. S. Hassan, E. S. Nossier, and A. G. Shalaby. "1,3,4-Triarylpyrazoles Containing 2-Thioxoimidazolidinones and Different Fused Systems: Synthesis and Antimicrobial Activity". Russian Journal of General Chemistry. 88 (12), 2646-2652(2018).
• Abd El-Galil E. Amr, Elsayed A. Elsayed, Mohamed A. Al-Omar, Hanan O. Badr Eldin, Eman S. Nossier and Mohamed M. Abdallah. "Design, Synthesis, Anticancer Evaluation and Molecular Modeling of Novel Estrogen Derivatives". Molecules. 24, 416(2019).
• Ibrahim F. Zeid, Neama A. Mohamed, Nagy M. Khalifa, Emad M. Kassem, Eman S. Nossier, Ahmed A. Salman, Khaled Mahmoud and Mohamed A. Al-Omar. "PI3K Inhibitors of Novel Hydrazide Analogues Linked 2-Pyridinyl Quinazolone Scaffold as Anticancer Agents". Journal of Chemistry. (2019), https://doi.org/10.1155/2019/6321573.
• Mohamed El-Naggar, Hanan A. Sallam, Safaa S. Shaban, Salwa S. Abdel-Wahab, Abd El-Galil E. Amr, Mohammad E. Azab, Eman S. Nossier and Mohamed A. Al-Omar. "Design, Synthesis, and Molecular Docking Study of Novel Heterocycles Incorporating 1,3,4-Thiadiazole Moiety as Potential Antimicrobial and Anticancer Agents". Molecules. 24, 1066(2019).
• Walaa S. El-serwy, Hanaa S. Mohamed, Weam S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Eman S. Nossier and Al Shimaa G. Shalaby. "Molecular Docking Study of Newly Synthesized Thiopyrimidines as Antimicrobial Agents Targeting DNA Gyrase Enzyme". Journal of Heterocyclic Chemistry. 56, 2027(2019).
• Asmaa F. Kassem, Gaber O. Moustafa, Eman S. Nossier, Hemat S. Khalaf, Marwa M. Mounier, Suliman A. Al-Yousef and Sabry Y. Mahmoud. " In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl)isophthalamide". Journal of Enzyme Inhibition and Medicinal Chemistry. 34( 1), 1247–1258(2019).
• Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Mohamed El-Naggar, Eman S. Nossier and Abd El-Galil E. Amr. "Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies". Journal of Enzyme Inhibition and Medicinal Chemistry. 34( 1), 1259–1270(2019).
• Ashraf S. Hassan, Ahmed A. Askar, Eman S. Nossier, Ahmed M. Naglah, Gaber O. Moustafa and Mohamed A. Al-Omar. "Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles". Molecules. 24, 3130 (2019).
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Sherifa Hasabelnaby, Eman A. Karam and Eman S. Nossier. "Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine-Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors". Molecules. 24, 3650 (2019).
• Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, Abd El-Galil E. Amr and Rashed N. Herqash. "Novel Synthesis of Pyrazole-Containing Thiophene, 2-Alkyloxypyridine and Thieno[2,3-d]Pyrimidine Scaffolds as Analgesic Agents". Bull. Chem. Soc. Ethiop. 2019, 33(3), 505-515.
• Magda M.F. Ismail, Hanan Gaber Abdulwahab, Eman Samir Nossier, Nagwan Galal El Menofy, Basma Abdelhameed Abdelkhalek. "Synthesis of Novel 2-Aminobenzothiazole Derivatives as Potential Antimicrobial Agents with Dual DNA Gyrase/Topoisomerase IV Inhibition". Bioorganic Chemistry 94, 103437 (2020).
• Abd El-Galil E. Amr, Randa E. Abdel Mageid, Mohamed El-Naggar, Ahmed M. Naglah, Eman S. Nossier, and Elsayed A. Elsayed. "Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl)Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A". Molecules 2020, 25, 1096.
• Dina H. Dawood, Eman S. Nossier, Mamdouh M. Ali, and Abeer E. Mahmoud. "Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase". Bioorganic Chemistry 2020,101, 103916.
• Heba E. Hashem, Abd El-Galil E. Amr, Eman S. Nossier, Elsayed A. Elsayed, Eman M. Azmy. "Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors". Molecules. 2020; 25(12):2766.
• H.S. Abd-Elghaffar, M.A. El-Hashash, S.F. Mohamed, A.A. Ibrahim, A.E. Amr, M.A. Al-Omar, E.S. Nossier. "Synthesis and Anti-Proliferative Activity of Novel Tricyclic Compounds Derived from 2-Substituted 1, 3-Indandione". Russian Journal of General Chemistry. 2020, 90(4):686-96.
• Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Abd El-Galil E. Amr, Mohamed A. Al-Omar, Eman S. Nossier, Elsayed A. Elsayed. "Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and in silico studies". Journal of Enzyme Inhibition and Medicinal Chemistry. 35( 1), 1491–1502(2020).
• Walaa S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Eman S. Nossier, Al Shimaa G. Shalaby. "Novel 5-Nitro Isatin derivatives as DNA Gyrase inhibitors: synthesis, antimicrobial evaluation, molecular docking, ADMET predictions and QSAR studies". Chem. Biol. Lett. 2020, 7(4), 197‐206.
• Nagy M. Khalifa, Hoda H. Fahmy, Eman S. Nossier, Mohamed A. Al-Omar, and Abd El-Galil E. Amr. "New Polysubstituted Pyrazole Derivatives: Synthesis and Cytotoxicity Studies". Russian Journal of General Chemistry 90(6), 1062–1068(2020).
• Fatma H. Mohamed, Ahmad M. Shalaby, Hanan A. Soliman, Ahmed Z. Abdelazem, Marwa M. Mounier, Eman S. Nossier, Gaber O. Moustafa. "Design, Synthesis and Molecular Docking Studies of Novel Cyclic Pentapeptides Based on Phthaloyl Chloride with Expected Anticancer Activity". Egypt.J.Chem. 63(5), 1723 - 1736(2020).
• Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Eman A. Karam, Eman S. Nossier and Marwa F. Ahmed. "Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors". Antibiotics 9, 695(2020).
• Walaa S. El-serwy, Hanaa S. Mohamed, Weam S. El-serwy, Neama A. Mohamed, Emad M. M. Kassem, Khaled Mahmoud and Eman S. Nossier. "Thiopyrimidine-5-carbonitrile Derivatives as VEGFR-2 Inhibitors: Synthesis, Anticancer Evaluation, Molecular Docking, ADME Predictions and QSAR Studies". ChemistrySelect 5, 15243– 15253 (2020).
• Reham R. Khattab, Asma K. Alshamari, Allam A. Hassan, Hussein H. Elganzory, Wael A. El-Sayed, Hanem M. Awad, Eman S. Nossier & Nasser A. Hassan. "Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazolethienopyrimidine hybrid glycosides targeting EGFR". Journal of Enzyme Inhibition and Medicinal Chemistry, 36 (1), 504–516 (2021).
• Somaia S. Abd El-Karim, Hanaa S. Mohamed, Mohamed F. Abdelhameed, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Eman S. Nossier. "Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity". Bioorganic Chemistry, 111, 104827 (2021).
• Eman A. Abd El-Meguid, Gaber O. Moustafa, Hanem M. Awad, Eman R. Zaki, and Eman S. Nossier. "Novel Benzothiazole Hybrids Targeting EGFR: Design, Synthesis, Biological Evaluation and Molecular Docking Studies". Journal of Molecular Structure, 130595(2021).
• Ashraf S. Hassan, Gaber O. Moustafa, Hanem M. Awad, Eman S. Nossier and Mohamed F. Mady. "Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids." ACS Omega 6, 12361−12374 (2021).
• Eman A. Fayed, Eman S. Nossier, Ahmed Atef, and Samar A. El-Kalyoubi. "In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors." Molecular Diversity 1-23 (2021).
• Ismail M.M. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Mohamed A. M. Gad-Elkareem, Manal M. Anwar, Eman S. Nossier. "New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies" Bioorganic Chemistry, 114, 105078 (2021).
• Israa A. Seliem, Siva S. Panda, Adel S. Girgis, Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, Eman S. Nossier, Fatma Rasslan, Aladdin M. Srour, Rajeev Sakhuja, Tarek S. Ibrahim, Zakaria K.M. Abdel-samii, Amany M.M. Al-Mahmoudy. "New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2" Bioorganic Chemistry, 114, 105117 (2021).
• Gaber O. Moustafa, Ahmed Shalaby, Ahmed M. Naglah, Marwa M. Mounier, Heba El-Sayed, Manal M. Anwar, and Eman S. Nossier. "Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives" Molecules 26(15), 4573 (2021).
• Reham R. Khattab, Allam A. Hassan, Dalia A. A. Osman, Farouk M. Abdel-Megeid, Hanem M. Awad, Eman S. Nossier, and Wael A. El-Sayed. "Synthesis, anticancer activity and molecular docking of new triazolo [4,5-d] pyrimidines based thienopyrimidine system and their derived N-glycosides and thioglycosides." Nucleosides, Nucleotides & Nucleic Acids, 1-24 (2021).
• Amira A. El-Sayed, Eman S. Nossier, Abdulrahman A. Almehizia, and Abd El-Galil E. Amr. "Design, synthesis, anticancer evaluation and molecular docking study of novel 2,4-dichlorophenoxymethyl-based derivatives linked to nitrogenous heterocyclic ring systems as potential CDK-2 inhibitors." Journal of Molecular Structure, 1247, 131285 (2022).
• Mohamed A. Hawata, Wael A. El-Sayed, Eman S. Nossier, and Adel A-H. Abdel-Rahman."Synthesis and Cytotoxic Activity of New Pyrimido [1, 2-c] quinazolines,[1, 2, 4] triazolo [4, 3-c] quinazolines and (quinazolin-4-yl)-1H-pyrazoles Hybrids." Biointerface Research in Applied Chemistry, 12(4), 5217–5233 (2022).
• Ismail M. M. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Mohamed A. M. Gad-Elkareem, Somaia S. Abd El-Karim and Eman S. Nossier, Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi-targeting kinase inhibitors. RSC Advances, 12, 561–577 (2022).
• Eman A. Abd El-Meguid, Eman M. Mohi El-Deen, Gaber O. Moustafa, Hanem M. Awad, and Eman S. Nossier. "Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1." Bioorganic Chemistry 105504, (2022).
• Heba S. A. El‐Zahabi, Eman S. Nossier, Safya M. Mousa, Heba Hassan, AL Shimaa G. Shalaby, and Reem K. Arafa. "Antibacterial and anticancer profiling of new benzocaine derivatives: Design, synthesis, and molecular mechanism of action." Archiv der Pharmazie e2100451(2022).
• Riham M. Bokhtia, Adel S. Girgis, Tarek S. Ibrahim, Fatma Rasslan, Eman S. Nossier, Reham F. Barghash, Rajeev Sakhuja, Eatedal H. Abdel-Aal, Siva S. Panda, and Amany MM Al-Mahmoudy. "Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates." Pharmaceuticals 15(2), 191 (2022).
• Mai E. Hussein, Osama G. Mohamed, Ahlam M. El Fishawy, Hesham I. El-Askary, Amira S. El Senousy, Ahmed A. El-Beih, Eman S. Nossier, Ahmed M. Naglah, Abdulrahman A. Almehizia, Ashootosh Tripathi and Ahmed A. Hamed. "Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques". Molecules 27(3), 1117 (2022).
• Heba E. Hashem, Abd El-Galil E. Amr, Eman S. Nossier, Manal M. Anwar, and Eman M. Azmy. "New Benzimidazole-, 1, 2, 4-Triazole-, and 1, 3, 5-Triazine-Based Derivatives as Potential EGFRWT and EGFRT790M Inhibitors: Microwave-Assisted Synthesis, Anticancer Evaluation, and Molecular Docking Study." ACS omega 7, 7155−7171 (2022).
• Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh and Asmaa F. Kassem. Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2. Molecules 27, 2047 (2022).
• Dina H. Dawood, Eman S. Nossier, Mohamed F. Abdelhameed, Gihan F. Asaad, and Sahar S. Abd El-Rahman. "Design, synthesis, anti-inflammatory evaluation and molecular docking of novel thiophen-2-ylmethylene-based derivatives as potential TNF-α production inhibitors." Bioorganic Chemistry 105726 (2022).
• Zahra M.Alamshany, Nada Y. Tashkandi, Ismail MM Othman, Manal M. Anwar, and Eman S. Nossier. "New thiophene, thienopyridine and thiazoline-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents and multitargeting kinase inhibitors." Bioorganic Chemistry 105964(2022).
• Heba SA Elzahabi, Eman S. Nossier, Rania A. Alasfoury, May El-Manawaty, Sara M. Sayed, Eslam B. Elkaeed, Ahmed M. Metwaly, Mohamed Hagras, and Ibrahim H. Eissa. "Design, synthesis, and anti-cancer evaluation of new pyrido [2, 3-d] pyrimidin-4 (3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers." Journal of Enzyme Inhibition and Medicinal Chemistry 37, no. 1, 1053-1076 (2022).
• Ismail MM. Othman, Zahra M. Alamshany, Nada Y. Tashkandi, Eman S. Nossier, Manal M. Anwar, and Hyam A. Radwan. "Chemical synthesis and molecular docking study of new thiazole, thiophene, and thieno[2,3-d]pyrimidine derivatives as potential antiproliferative and antimicrobial agents." Journal of Molecular Structure 133926 (2022).
• Eman S. Nossier, Rania A. Alasfoury, Mohamed Hagras, May El-Manawaty, Sara M. Sayed, Ibrahim M. Ibrahim, Hazem Elkady, Ibrahim H. Eissa, and Heba SA Elzahabi. "Modified pyrido [2, 3-d] pyrimidin-4 (3H)-one derivatives as EGFRWT and EGFRT790M inhibitors: Design, synthesis, and anti-cancer evaluation." Journal of Molecular Structure 133971(2022).
• Eman M. Mohi El‐Deen, Eman S. Nossier and Eman A. Karam. "New Quinazolin‐4(3H)‐one Derivatives Incorporating Hydrazone and Pyrazole Scaffolds as Antimicrobial Agents Targeting DNA Gyraze Enzyme" Scientia Pharmaceutica 90, 52 (2022).
• Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, and Asmaa F Kassem. "New 1, 2, 3-Triazole-Coumarin-Glycoside Hybrids and Their 1, 2, 4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation." Molecules 27(17) 5688 (2022).
• Hussein H. Elganzory, Fahad M. Alminderej, Mohamed N. El-Bayaa, Hanem M. Awad, Eman S. Nossier, and Wael A. El-Sayed. "Design, Synthesis, Anticancer Activity and Molecular Docking of New 1, 2, 3-Triazole-Based Glycosides Bearing 1, 3, 4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds." Molecules 27 (20) 6960 (2022).
• Aladdin M. Srour, Dina H. Dawood, Eman S. Nossier, Riham A. El-Shiekh, Abeer E. Mahmoud, Amal G. Hussien, Mervat M. Omran, and Mamdouh M. Ali. "Design, Synthesis and Molecular Docking Simulation of Oxindole-Based Derivatives with Dual VEGFR-2 and Cholinesterase Inhibitory Activities." Journal of Molecular Structure 1271, 134130 (2023).
• Rania A. Alasfoury, Eman S. Nossier, May El-Manawaty, and Heba SA Elzahabi. "Novel Pyrido-Thiazolo-Pyrimidinone Hybrids targeting EGFRWT and EGFRT790M: Design, Synthesis, Anticancer Activity and docking simulation." Azhar International Journal of Pharmaceutical and Medical Sciences 3(1) 112-119 (2023).
• Zahra M. Alamshany, Eman M. Algamdi, Ismail M. M. Othman, Manal M. Anwar and Eman S. Nossier "New pyrazolopyridine and pyrazolothiazole-based compounds as anti-proliferative agents targeting c-Met kinase inhibition: design, synthesis, biological evaluation, and computational studies" RSC Advances 13, 12889–12905 (2023).
• Asmaa F. Kassem, Mohamed A. Omar, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Novel Pyridine-Thiazolidinone-Triazole Hybrid Glycosides Targeting EGFR and CDK-2: Design, Synthesis, Anticancer Evaluation, and Molecular Docking Simulation." Journal of Molecular Structure 1294, 136358 (2023).
• Dina H. Dawood, Manal M. Sayed, Sally TK Tohamy, and Eman S. Nossier. "New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies." ACS Omega 8, 39250−39268 (2023).
• Heba E. Hashem, Abd El-Galil E. Amr, Abdulrahman A. Almehizia, Ahmed M. Naglah, Benson M. Kariuki, Heba A. Eassa and Eman S. Nossier. "Nanoparticles of a Pyrazolo-Pyridazine Derivative as Potential EGFR and CDK-2 Inhibitors: Design, Structure Determination, Anticancer Evaluation and In Silico Studies." Molecules 28, 7252 (2023).
• Dina H. Dawood, Dalia O. Saleh, Gehad A. Abdel Jaleel and Eman S. Nossier. " New Chromone-Thiazolopyrimidine Hybrids as Potent TNF-α, IL-6 and PGE2 Inhibitors: Synthesis, Anti-Inflammatory Evaluation and Molecular Modeling Studies." Polycyclic Aromatic Compounds 44(10), 6564–6588 (2024).
• Nossier, E.S., Khalifa, N.M., Fahmy, H.H., Ismail, M.M.F., El-Sahrawy, H.M. and Ali, M.M.,. Novel Bipyrazole Targeting Dual CDK-2 and VEGFR-2 Kinases: Synthesis, Anticancer Evaluation, and In Silico Studies. Russian Journal of Bioorganic Chemistry, 50(1), 227-238 (2024).
• Rasha Z. Batran, , Eman Y. Ahmed, Eman S. Nossier, Hanem M. Awad, and Nehad A. Abdel Latif. "Anticancer activity of new triazolopyrimidine linked coumarin and quinolone hybrids: synthesis, molecular modeling, TrkA, PI3K/AKT and EGFR inhibition." Journal of Molecular Structure 137790 (2024).
• Fatma H Mohamed, Gaber O Moustafa, Eman Nossier, and Marwa Mounier. "In Vitro Anticancer Potentiality and Molecular Modelling Study of Novel Cyclic Pentapeptides based on 1,2-benzenedicarbonyl chloride." Egyptian Journal of Chemistry 67, no. 13 (2024): 567-576.
• Fatma H Mohamed, Gaber O Moustafa, Eman Nossier, and Marwa Mounier. "Design, Synthesis and Molecular Docking Studies of Novel Amino Acids and Peptide Derivatives Based on Phthaloyl Chloride With Expected Anticancer Activity." Egyptian Journal of Chemistry 67, no. 13 (2024): 577-587.
• Eman S. M. Elsenbawy, Zafer S. Alshehri, Nouf A. Babteen, Adel A.-H. Abdel-Rahman, Mai A. El-Manawaty, Eman S. Nossier, Reem K. Arafa and Nasser A. Hassan "Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidine Derivatives." Molecules 29, 1067 (2024).
• Asmaa F. Kassem, Ahmed Younis, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Pyridine-Based Glycosides Bearing 1, 2, 4-Triazole and Their 1, 3, 4-oxadiazole analogues as Potential EGFR and CDK-2 Inhibitors: Design, Synthesis, Antiproliferative Activity and In Silico Studies." Journal of Molecular Structure 138741(2024).
• Yasmin S. Sheta, Marwa T. Sarg, Fatma G. Abdulrahman, Eman S. Nossier, and Ebtehal M. Husseiny. "Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights." Bioorganic Chemistry 107471(2024).
• Dina Dawood, Nesma Abo El-Nasr, Passant Mustafa, Dalia Saleh, Omar Farid, and Eman Nossier. "Synthesis and molecular modeling study of new pyrimidine-based derivatives as anticonvulsant agents." Egyptian Journal of Chemistry (2024).
• Hebat-Allah S. Abbas, Eman S. Nossier, May A. El-Manawaty, and Mohamed N. El-Bayaa. "New sulfonamide-based glycosides incorporated 1, 2, 3-triazole as cytotoxic agents through VEGFR-2 and carbonic anhydrase inhibitory activity." Scientific reports 14, no. 1, 13028 (2024).
• Zahra M. Alamshany1, Eman S. Nossier. “New thiazole Derivatives Linked to Pyridine, Fused Pyridine, Pyrimidine and Thiazolopyrimidine Scaffolds with Potential dual Anticancer and Antimicrobial Activities: Design, Synthesis and Docking Simulation” Journal of Molecular Structure 138973 (2024).
• Gaber O. Moustafa, , Atef Kalmouch, Somaia S. Abd El-Karim, Eman S. Nossier, Marwa M. Mounier, Heba El-Sayed, Abdulrahman A. Almehizia, Ahmed M. Naglah, and Amer A. Zen. "Target-based anticancer glycyrrhetinic derivatives: Design, synthesis, biological assessment and molecular docking studies." Bulletin of the Chemical Society of Ethiopia 38, no. 5, 1369-1392 (2024).
• Dania Alweet, Mohamed El-Bayaa, Sobhi Gomha, Fahad Alminderej, Eman S. Nossier, Wael A El-Sayed, and Ahd Alenazy. "Synthesis, Molecular Docking and Anticancer Activity of New Pyridyl-1, 2, 4-Triazole-Thioglycosides and Their Pyridyl-[1, 2, 4] triazolo [1, 5-a] pyridine-Glycoside Analogues." Egyptian Journal of Chemistry (2024).
• Adel A-H. Abdel-Rahman, Mohamed N. El-Bayaa, Asmaa Sobhy, Eman M. El-Ganzoury, Eman S. Nossier, Hanem M. Awad, and Wael A. El-Sayed. "Novel quinazolin-4-one based derivatives bearing 1, 2, 3-triazole and glycoside moieties as potential cytotoxic agents through dual EGFR and VEGFR-2 inhibitory activity." Scientific Reports 14, no. 1, 24980 (2024).
• Aladdin M. Srour, Eman S. Nossier, Najla A. Altwaijry, Safeya M. Mousa, Hanem M. Awad, and Heba SA Elzahabi. "New pyrano-pyridine conjugates as potential anticancer agents: design, synthesis and computational studies." Future Medicinal Chemistry 16, 2567–2582 (2024).
• Nadia M. Hamdy, Emad B. Basalious, Mona G. El-Sisi, Maha Nasr, Ahmed M. Kabel, Eman S. Nossier, and Ashraf H. Abadi. "Advancements in current one-size-fits-all therapies compared to future treatment innovations for better improved chemotherapeutic outcomes: a step-toward personalized medicine." Current Medical Research and Opinion 1-34, (2024).
• Aisha A. Alsfouk, , Ismail MM Othman, Manal M. Anwar, Walaa A. Alshareef, Asmaa Saleh, and Eman S. Nossier. "Synthesis and computational studies of new pyridine, pyrazole, pyran, and pyranopyrimidine-based derivatives of potential antimicrobial activity as DNA gyrase and topoisomerase IV inhibitors." Journal of Molecular Structure 1319, 139528 (2025).
• Wael A. El-Sayed, Mohammed SM Aladl, Eman Nossier, and Alaa MM Younis. "Chemistry of Persistent Organic Pollutants (POPs): Distribution, Environmental Impact and Mitigation Approaches." Egyptian Journal of Chemistry 68 (9), 663-677 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Manal M. Anwar, Asmaa Saleh, and Eman S. Nossier. "Design, synthesis, and in silico studies of new quinazolinones tagged thiophene, thienopyrimidine, and thienopyridine scaffolds as antiproliferative agents with potential p38α MAPK kinase inhibitory effects." RSC advances 15, no. 2 (2025): 1407-1424.
• Dina Dawood, Dalia Saleh, Nesma Abo El-Nasr, Passant Mustafa, Omar Farid, and Eman Nossier. "Synthesis and molecular modeling study of new pyrimidine-based derivatives as anticonvulsant agents." Egyptian Journal of Chemistry 68, no. 1 (2025): 109-122.
• Hagar S. El-Hema, Sara M. Soliman, Wagdy El-Dougdoug, Mohamed HM Ahmed, Abdelmotaal Abdelmajeid, Eman S. Nossier, Modather F. Hussein et al. "Design, Characterization, Antimicrobial Activity, and In Silico Studies of Theinothiazoloquinazoline Derivatives Bearing Thiazinone, Tetrazole, and Triazole Moieties." ACS Omega 10, 9703−9717 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Manal M. Anwar, Asmaa Saleh, Nada Y. Tashkandi, and Eman S. Nossier. "New quinazolinone-based heterocyclic compounds as promising antimicrobial agents: development, DNA gyrase B/topoisomerase IV inhibition activity, and in silico computational studies." Journal of Molecular Structure 1344,142953 (2025).
• Safeya M. Mousa, Eman S. Nossier, Aladdin M. Srour, Hanem M. Awad, and Heba SA Elzahabi. "Design, Synthesis, Cytotoxicity, and Docking Study of New Pyrano [3, 2–c] Pyridine-Based Derivatives." Azhar International Journal of Pharmaceutical and Medical Sciences 5, no. 2 57-65 (2025).
• Ahmad E. Mohamed, Walid E. Elgammal, Ahmed G. Ibrahim, Hamdy M. Dawaba, Eman S. Nossier, and Aya M. Dawaba. "Thiadiazole chitosan conjugates as a novel cosmetic ingredient for rinse-off hair conditioners: design, formulation, characterization and in silico-molecular docking studies." BMC Chemistry 19, 104 (2025).
• Eman S. Nossier, Manal M. Anwar, and Mohamed Ayman El-Zahabi. "Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches." Molecular Diversity 1-28 (2025).
• Ahmed M. Hussein, Walaa I. EL‐Sofany, Fahad M. Alminderej, Abuzar EAE Albadri, Hanem M. Awad, Eman S. Nossier, and Wael A. El‐Sayed. "New Thiadiazole‐Triazole Hybrid Glycosides as Potential EGFR and VEGFR‐2 Inhibitors: Synthesis, Anticancer Activity, and Docking Simulation." ChemistrySelect 10, no. 28, e04887 (2025).
• Sara M. Soliman, Adel A.-H. Abdel-Rahman, Eman S. Nossier, Modather F. Hussein, Amr Sabry & Hagar S. El-Hema. "Design, antiproliferative potency, and in silico studies of novel 5-methylfuran-3-yl)thio)-3- phenylquinazolin-4(3H)-one based derivatives as potential EGFR inhibitors" Scientific Reports 15, 27992 (2025).
• Aisha A. Alsfouk, Ismail MM Othman, Hamdi MD Nasr, Esam A. Ishak, Asmaa Saleh, and Eman S. Nossier. "Synthesis, Characterization, Computational Studies and In Vitro Biological Effects of Novel Pyrazoles, Pyridazines, Thiazoles Containing a Quinazoline Scaffold." ChemistrySelect 10( 30), e01583 (2025).
• Hagar S. El-Hema, Mohamed F. Mady, Adel A.-H. Abdel-Rahman, Eman S. Nossier, Ahmed F. El-Sayed, Amr Sabry, Murad El-Feky, Mohamed A. Hawata. “Novel pyrimidopyridothiazine based derivatives as potential anticancer and antibacterial agents: A step towards design and synthesis of multi-targeted therapeutics” Journal of Molecular Structure1349, 143790 (2026).
• Manar M. Saber, Reham R. Khattab, Sherin H. Pasha, Moshira M. Abd-El Wahed, Ahmed A. El-Sayed, Adel AH Abdel-Rahman, Eman S. Nossier, and Nasser A. Hassan. "Novel Glycosylated Dihydropyridine-Based Nanoformulations as EGFR Inhibitors." Egyptian Journal of Chemistry (2025).