
Awards
Degrees:
2012
Doctorate Structural, Cell and Molecular Biology
I am a molecular virologist
Publications resulting from Research
1. Ray, U. 2016. Virus like nanoparticles: Display matters Proceedings of Indian National Science Academy (Accepted) (Review)
2. Ray, U., Cinque, P., Gerevini, S., Longo, V., Lazzarin, A., Schippling, S., Martin, R., Buck, C.B., and Pastrana, D.V. 2015. JC polyomavirus mutants escape antibody-mediated neutralization. Science Translational Medicine. 7(306):306ra151(PMID:26400912)
3. Ray, U., Roy, C. L., Kumar, A. , Mani, P., Joseph, A. P., Sudha, G., Sarkar, D. P., Srinivasan, N., and Das, S. 2013. Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: A novel therapeutic strategy. Molecular Therapy (Nature Publishing Group). 21(1):57-67. (PMID:22910295)
4. Ray, U., Ray, P. S. and Das, S. 2012 Ribosome-RNA interaction: A potential target for developing antiviral against hepatitis C virus. Current Science. Vol 102; No. 3. (Review)
5. Ray, U., and Das, S. 2011. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus. Scientific Reports (Nature Publishing Group) 1:1. (PMID:22355520)
6. *Mondal, T., *Ray, U., Manna, A. K., Gupta, R., Roy, S., and Das, S. 2008. Structural determinant of human La protein critical for internal initiation of translation of hepatitis C virus RNA. Journal of Virology 82:11927-38. (*joint first authors) (PMCID:18829760) (Cover page article)
Second Author
7. Kumar, A., Manna, A. K., Ray, U., Mullick, R., Basu, G., Das, S. and Roy, S. 2014.Specific sequence of a beta-turn in human La protein may contribute to species specificity of Hepatitis C virus. Journal of Virology 88(8):4319-27 (PMID:24478427)
8. Pastrana, D. V., Ray, U., Magaldi, T. G., Schowalter, R., M., Cuburu, N., and Buck, C. B. 2013. BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. Journal of Virology 87(18):10105-13 (PMID:23843634)
9. Kumar, A., Ray, U. and Das, S. 2013. Human La protein Interaction with GCAC near the initiator AUG enhances HCV RNA replication by Promoting Linkage Between 5'-and 3'- untranslated regions. Journal of Virology 87(12):6713-26 (PMID:23552417)
10. Manna, A. K., Kumar, A., Ray, U., Das, S., Basu, G. and Roy, S. 2013. A cyclic peptide mimic of an RNA recognition motif of human La protein is a potent inhibitor of hepatitis C virus. Antiviral Research 97(3):223-226. (PMID:23291201)
11. Ravikumar, Y. S., Ray, U., Nandhitha, M., Perween, A., Raja Naika, H., Khanna, N. and Das, S. 2011. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Virus Research 158:89-97. (PMID:21440018)
Patents
1. Treating or Inhibiting JC polyomavirus infection and JC polyomavirus-associated progressive multifocal leukoencephalopathy. Christopher Buck, Upasana Ray, Diana Pastrana (US Application number: 61/919,043)
2. Compositions, method and formulations for peptide based inhibitors of Hepatitis C virus replication. Saumitra Das, Upasana Ray, Debi P. Sarkar, Chaitrali Laha Roy, N. Srinivasan. (Application number: 4033/CHE/2011 A)
3. Small antiviral peptides against Hepatitis C virus. Saumitra Das, Siddhartha Roy, Upasana Ray, Tanmoy Mondal, Asit Kumar Manna, Romi Gupta. (US Application number: 2009/0233868A1)
Book Chapters
1. Upasana Ray, Saumitra Das (2009) Role of Human La protein in Translation and Replication of Hepatitis C Virus. Mechanisms of Microbial Pathogenesis. TATA McGraw-Hill publication.
2. Upasana Ray, Chaitrali Laha Roy, Saumitra Das (2011) Viruses and our fight against them. UGC-sponsored national seminar on microbiology: development and challenges in basic and applied research (organized by department of microbiology, Ramakrishna Mission Vidyamandira, Belur Math in collaboration with Bose Institute, Kolkata)
Research Highlight/ Coverage
1. Therapeutic opportunity knocks (2015): Science (Vol. 349; Issue: 6255; page-1501)
2. Studies propose vaccination for troublemaking virus (2015): Multiple Sclerosis Discovery Forum
3. Closing “blind spots” in patients’ immune response to lethal brain infection (2015): EurekaAlert
4. Researchers work towards vaccination for PML (2015): MS UN Master Cylinder (Breaking News)
5. Possible JC virus vaccination offers important implications for MS treatment (2015): Multiple Sclerosis News Today
6. Hep C viral switch (2011): Nature India (doi:10.1038/nindia.2011.83)
2. Ray, U., Cinque, P., Gerevini, S., Longo, V., Lazzarin, A., Schippling, S., Martin, R., Buck, C.B., and Pastrana, D.V. 2015. JC polyomavirus mutants escape antibody-mediated neutralization. Science Translational Medicine. 7(306):306ra151(PMID:26400912)
3. Ray, U., Roy, C. L., Kumar, A. , Mani, P., Joseph, A. P., Sudha, G., Sarkar, D. P., Srinivasan, N., and Das, S. 2013. Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: A novel therapeutic strategy. Molecular Therapy (Nature Publishing Group). 21(1):57-67. (PMID:22910295)
4. Ray, U., Ray, P. S. and Das, S. 2012 Ribosome-RNA interaction: A potential target for developing antiviral against hepatitis C virus. Current Science. Vol 102; No. 3. (Review)
5. Ray, U., and Das, S. 2011. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus. Scientific Reports (Nature Publishing Group) 1:1. (PMID:22355520)
6. *Mondal, T., *Ray, U., Manna, A. K., Gupta, R., Roy, S., and Das, S. 2008. Structural determinant of human La protein critical for internal initiation of translation of hepatitis C virus RNA. Journal of Virology 82:11927-38. (*joint first authors) (PMCID:18829760) (Cover page article)
Second Author
7. Kumar, A., Manna, A. K., Ray, U., Mullick, R., Basu, G., Das, S. and Roy, S. 2014.Specific sequence of a beta-turn in human La protein may contribute to species specificity of Hepatitis C virus. Journal of Virology 88(8):4319-27 (PMID:24478427)
8. Pastrana, D. V., Ray, U., Magaldi, T. G., Schowalter, R., M., Cuburu, N., and Buck, C. B. 2013. BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. Journal of Virology 87(18):10105-13 (PMID:23843634)
9. Kumar, A., Ray, U. and Das, S. 2013. Human La protein Interaction with GCAC near the initiator AUG enhances HCV RNA replication by Promoting Linkage Between 5'-and 3'- untranslated regions. Journal of Virology 87(12):6713-26 (PMID:23552417)
10. Manna, A. K., Kumar, A., Ray, U., Das, S., Basu, G. and Roy, S. 2013. A cyclic peptide mimic of an RNA recognition motif of human La protein is a potent inhibitor of hepatitis C virus. Antiviral Research 97(3):223-226. (PMID:23291201)
11. Ravikumar, Y. S., Ray, U., Nandhitha, M., Perween, A., Raja Naika, H., Khanna, N. and Das, S. 2011. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Virus Research 158:89-97. (PMID:21440018)
Patents
1. Treating or Inhibiting JC polyomavirus infection and JC polyomavirus-associated progressive multifocal leukoencephalopathy. Christopher Buck, Upasana Ray, Diana Pastrana (US Application number: 61/919,043)
2. Compositions, method and formulations for peptide based inhibitors of Hepatitis C virus replication. Saumitra Das, Upasana Ray, Debi P. Sarkar, Chaitrali Laha Roy, N. Srinivasan. (Application number: 4033/CHE/2011 A)
3. Small antiviral peptides against Hepatitis C virus. Saumitra Das, Siddhartha Roy, Upasana Ray, Tanmoy Mondal, Asit Kumar Manna, Romi Gupta. (US Application number: 2009/0233868A1)
Book Chapters
1. Upasana Ray, Saumitra Das (2009) Role of Human La protein in Translation and Replication of Hepatitis C Virus. Mechanisms of Microbial Pathogenesis. TATA McGraw-Hill publication.
2. Upasana Ray, Chaitrali Laha Roy, Saumitra Das (2011) Viruses and our fight against them. UGC-sponsored national seminar on microbiology: development and challenges in basic and applied research (organized by department of microbiology, Ramakrishna Mission Vidyamandira, Belur Math in collaboration with Bose Institute, Kolkata)
Research Highlight/ Coverage
1. Therapeutic opportunity knocks (2015): Science (Vol. 349; Issue: 6255; page-1501)
2. Studies propose vaccination for troublemaking virus (2015): Multiple Sclerosis Discovery Forum
3. Closing “blind spots” in patients’ immune response to lethal brain infection (2015): EurekaAlert
4. Researchers work towards vaccination for PML (2015): MS UN Master Cylinder (Breaking News)
5. Possible JC virus vaccination offers important implications for MS treatment (2015): Multiple Sclerosis News Today
6. Hep C viral switch (2011): Nature India (doi:10.1038/nindia.2011.83)
DNA tumor virus meeting
2025
American Society for Virology (ASV) meeting
2025
DNA tumor virus meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
Indo-Singapore meeting
2025
2nd Virology meeting
2025
RNA 2010
2025
ICGEB-IUBMB workshop ‘Human RNA Viruses’
2025
79th Annual Meeting of the Society of Biological Chemists (Theme: Regulation of biochemical and cellular processes in diverse systems)
2025
IISc centenary symposium on biology and pathogenesis of viruses: Molecular insights
2025
IISc Centenary Symposium on ‘Mechanisms of microbial pathogenesis’
2025
15th international symposium on Hepatitis C Virus and related viruses
2025
77th Annual Meeting of the Society of Biological Chemists (Theme: impact of basic and translational research on medicine, agriculture and industry)
2025
Guest lecture
2025
Guest lecture
2025
DNA tumor virus meeting
2025
American Society for Virology (ASV) meeting
2025
DNA tumor virus meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
Indo-Singapore meeting
2025
2nd Virology meeting
2025
RNA 2010
2025
ICGEB-IUBMB workshop ‘Human RNA Viruses’
2025
79th Annual Meeting of the Society of Biological Chemists
2025
IISc centenary symposium on biology and pathogenesis of viruses: Molecular insights
2025
IISc Centenary Symposium on ‘Mechanisms of microbial pathogenesis’
2025
15th international symposium on Hepatitis C Virus and related viruses
2025
77th Annual Meeting of the Society of Biological Chemists
2025
DNA Tumor virus meeting
2025