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Member Profile

Membership type: full

Sandra Ayuk

Country of origin: Cameroon Currently in: South Africa, Johannesburg General field of specialization: Medical and Health Sciences incl Neurosciences
Academic Background

Degrees

2018 Doctorate Medical and Health Sciences incl Neurosciences
2013 Master Medical and Health Sciences incl Neurosciences
2011 Undergraduate Medical and Health Sciences incl Neurosciences
Research and Profession

Current Research Activities

Medical and Health Sciences incl Neurosciences

Specialist in laser therapy and diabetic wound healing. Currently a post doctorate researcher in the University of Johannesburg working on the effect of photodynamic therapy associated with the mTOR pathway on cancer cell lines to develop a better alternative treatment for cancer.


Publications resulting from Research: 


Sandra M Ayuk and Heidi Abrahamse (2019) mTOR Signalling pathway in Cancer Targets Photodynamic therapy in vitro, Cells- 8(5), Published May 9, DOI: 10.3390/cells8050431

Nicolette Houreld, Sandra Ayuk, Heidi Abrahamse (2018) Cell Adhesion Molecules are Mediated by Photobiomodulation at 660 nm in Diabetic Wounded Fibroblast Cells, Cells, 7(4): 30, published 16 April 2018. https//doi: 10.3390/cells7040030.

Ayuk, S.M., Abrahamse, H. and Houreld, N. (2018). Effect of 660 nm visible red light on cell proliferation and viability in diabetic models in vitro under stressed conditions, Lasers in Medical Science, https://doi.org/10.1007/s10103-017-2432-2, published 8 March 2018

Ayuk, S.M., Abrahamse, H. and Houreld, N.N. (2018) Photobiomodulation alters matrix protein activity in stressed fibroblast cells in vitro, Journal of Biophotonics, 11(3).https://doi: 10.1002/jbio.201700127, published 7 Nov 2017

S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) The role of matrix metalloproteinases (MMP) in diabetic wound healing in relation to photobiomodulation (PBM), Journal for Diabetes Research Volume 2016, Article ID 2897656, 9 pages, https://dx.doi.org/10.1155/2016/2897656, 8 May 2016

S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) The role of laser phototherapy (photobiostimulation) on cell adhesion molecules in diabetic wounded fibroblasts in vitro, Journal for Photochemistry and Photobiology B:Biology 161: 368–374. dx.doi.org/10.1016/j.jphotobiol.2016.05.027, published 1 Jun 2016

Ayuk, S.M., Houreld, N.N. and Abrahamse, H. (2014) Laser Irradiation Alters the Expression Profile of Genes Involved in the Extracellular Matrix In Vitro, International Journal of Photoenergy, 2014 (2014), Article ID 604518, 17 pages, https://dx.doi.org/10.1155/2014/604518, Published 23 Jun 2014

Houreld, N., Ayuk S. and Abrahamse, H. (2014) Expression of Genes involved in Wound Healing in Response to Irradiation at 660 nm. Journal of Photochemistry and Photobiology B: Biology 130:146-152. doi: 10.1016/j.jphotobiol.2013.11.018. Published 27 Nov 2013

Ayuk, S.M., Houreld N.N. and Abrahamse H. (2012) Response of Low Intensity Laser Irradiation on Collagen Production in Diabetic Wounded Fibroblast In Vitro Diabetes Technology and Therapeutics. 14(12):1110-1117. https://doi.org/10.1089/dia.2012.0125, Published 11 Oct 2012

S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) Gene expression changes in diabetic wound healing as induced by photobiostimulation in vitro, in The Proceedings of the 60th Annual Conference of the South African Institute of Physics (SAIP2015), edited by Makaiko Chithambo (RU) and André Venter (NMMU) (2015), pp. 244-248. ISBN: 978-0-620-70714-5.

Ayuk, S.M., Houreld, N.N. and Abrahamse, H. (2013) Response of low intensity laser irradiation on collagen production in diabetic wounded fibroblast in vitro. Proceedings of the 57th annual conference of the South African Institute of Physics. ISBN: 978-1-77592-070-0. pp.283-287 (Published 12 Dec 2014).

Houreld N.N. and Ayuk S.M. (2017) Influence of Photobiomodulation (Low-Level Laser Therapy) on Diabetic Wound Healing. In: Low-Level Laser Therapy: History, Mechanisms, and Medical Uses. NOVA publishers, New York, ISBN: 978-1-53613-227-4

Ayuk S M. Role of Low Intensity Laser Irradiation in Wound healing in vitro. Houreld N N and Abrahamse H. (Eds), Lambert Academic publishing, Omniscriptum Publishing group, Balti, Moldova 2018, accepted 28 Mar 2018. Final Submission 6 July 2018



Current profession


Prizes, Grants and Awards

Other Awards

Aug 2018
Best Women in Science
Dynamic Ladyz African Women in Diaspora Award in recognition of research output and contribution to the Society. This award was given to a Woman who is passionate about her research and disseminates knowledge in the community, local and international conferences. A woman develops, motivates and supports other young Women to achieve their academic and professional goals by organising mentorship programs and also creating platforms for other young researchers to grow. A woman who is dedicated to her community and seeing how her research can impact as such.
Jul 2016
3 min thesis presentation award- second prize
Three minutes thesis presentation in the University of Johannesburg, Faculty of health sciences
Sep 2016
Travel Grant
Recipient of NRF Knowledge, Interchange & Collaboration (KIC) Scientific travel grant to present in the World Association of Laser therapy conference held in Sao Paolo, Brazil
Jan 2018
Global Excellence and Stature award
Bursary award given for academic excellence. Also received in 2014, 2015, 2016 and 2017
Oct 2014
Merit Award
2nd Best Oral presentation in the African Laser Student's Workshop held in Morocco
Sep 2014
Travel Grant
Travel grant awarded for the best abstract to attend the World Association of Laser Therapy conference in USA.
Jan 2014
Merit Award
Masters with distinction awarded from 2014-2016
Oct 2017
Deans Merit award of distinction
Overall Best performing student in the laser research department, faculty of health sciences. Also awarded in 2012, 2013 and 2016
Oct 2012
Merit award
Best Poster presentation in the African Laser student Workshop held in Windhoek, Namibia
Oct 2013
Special Residential Award
Outstanding Postgraduate Work by the Student Accommodation and Residence Life
Oct 2012
Merit Award
Good Leadership by the Student Accommodation and Residence life. Was also awarded in 2010 and 2011
Jan 2017
Bursary Award
Awarded by the African Laser Centre to study Masters and PhD. Also awarded in 2012, 2013, 2014 and 2015