Sandra AyukCountry of origin: Cameroon Currently in: South Africa, Johannesburg General field of specialization: Medical and Health Sciences incl Neurosciences
Degrees2018 Doctorate Medical and Health Sciences incl Neurosciences2013 Master Medical and Health Sciences incl Neurosciences2011 Undergraduate Medical and Health Sciences incl Neurosciences
Current Research Activities
Medical and Health Sciences incl Neurosciences
Specialist in laser therapy and diabetic wound healing. Currently a post doctorate researcher in the University of Johannesburg working on the effect of photodynamic therapy associated with the mTOR pathway on cancer cell lines to develop a better alternative treatment for cancer.
Publications resulting from Research:
Sandra M Ayuk and Heidi Abrahamse (2019) mTOR Signalling pathway in Cancer Targets Photodynamic therapy in vitro, Cells- 8(5), Published May 9, DOI: 10.3390/cells8050431
Nicolette Houreld, Sandra Ayuk, Heidi Abrahamse (2018) Cell Adhesion Molecules are Mediated by Photobiomodulation at 660 nm in Diabetic Wounded Fibroblast Cells, Cells, 7(4): 30, published 16 April 2018. https//doi: 10.3390/cells7040030.
Ayuk, S.M., Abrahamse, H. and Houreld, N. (2018). Effect of 660 nm visible red light on cell proliferation and viability in diabetic models in vitro under stressed conditions, Lasers in Medical Science, https://doi.org/10.1007/s10103-017-2432-2, published 8 March 2018
Ayuk, S.M., Abrahamse, H. and Houreld, N.N. (2018) Photobiomodulation alters matrix protein activity in stressed fibroblast cells in vitro, Journal of Biophotonics, 11(3).https://doi: 10.1002/jbio.201700127, published 7 Nov 2017
S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) The role of matrix metalloproteinases (MMP) in diabetic wound healing in relation to photobiomodulation (PBM), Journal for Diabetes Research Volume 2016, Article ID 2897656, 9 pages, https://dx.doi.org/10.1155/2016/2897656, 8 May 2016
S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) The role of laser phototherapy (photobiostimulation) on cell adhesion molecules in diabetic wounded fibroblasts in vitro, Journal for Photochemistry and Photobiology B:Biology 161: 368–374. dx.doi.org/10.1016/j.jphotobiol.2016.05.027, published 1 Jun 2016
Ayuk, S.M., Houreld, N.N. and Abrahamse, H. (2014) Laser Irradiation Alters the Expression Profile of Genes Involved in the Extracellular Matrix In Vitro, International Journal of Photoenergy, 2014 (2014), Article ID 604518, 17 pages, https://dx.doi.org/10.1155/2014/604518, Published 23 Jun 2014
Houreld, N., Ayuk S. and Abrahamse, H. (2014) Expression of Genes involved in Wound Healing in Response to Irradiation at 660 nm. Journal of Photochemistry and Photobiology B: Biology 130:146-152. doi: 10.1016/j.jphotobiol.2013.11.018. Published 27 Nov 2013
Ayuk, S.M., Houreld N.N. and Abrahamse H. (2012) Response of Low Intensity Laser Irradiation on Collagen Production in Diabetic Wounded Fibroblast In Vitro Diabetes Technology and Therapeutics. 14(12):1110-1117. https://doi.org/10.1089/dia.2012.0125, Published 11 Oct 2012
S.M. Ayuk., H. Abrahamse and N.N. Houreld (2016) Gene expression changes in diabetic wound healing as induced by photobiostimulation in vitro, in The Proceedings of the 60th Annual Conference of the South African Institute of Physics (SAIP2015), edited by Makaiko Chithambo (RU) and André Venter (NMMU) (2015), pp. 244-248. ISBN: 978-0-620-70714-5.
Ayuk, S.M., Houreld, N.N. and Abrahamse, H. (2013) Response of low intensity laser irradiation on collagen production in diabetic wounded fibroblast in vitro. Proceedings of the 57th annual conference of the South African Institute of Physics. ISBN: 978-1-77592-070-0. pp.283-287 (Published 12 Dec 2014).
Houreld N.N. and Ayuk S.M. (2017) Influence of Photobiomodulation (Low-Level Laser Therapy) on Diabetic Wound Healing. In: Low-Level Laser Therapy: History, Mechanisms, and Medical Uses. NOVA publishers, New York, ISBN: 978-1-53613-227-4
Ayuk S M. Role of Low Intensity Laser Irradiation in Wound healing in vitro. Houreld N N and Abrahamse H. (Eds), Lambert Academic publishing, Omniscriptum Publishing group, Balti, Moldova 2018, accepted 28 Mar 2018. Final Submission 6 July 2018
Other AwardsAug 2018Best Women in ScienceDynamic Ladyz African Women in Diaspora Award in recognition of research output and contribution to the Society. This award was given to a Woman who is passionate about her research and disseminates knowledge in the community, local and international conferences. A woman develops, motivates and supports other young Women to achieve their academic and professional goals by organising mentorship programs and also creating platforms for other young researchers to grow. A woman who is dedicated to her community and seeing how her research can impact as such.Jul 20163 min thesis presentation award- second prizeThree minutes thesis presentation in the University of Johannesburg, Faculty of health sciencesSep 2016Travel GrantRecipient of NRF Knowledge, Interchange & Collaboration (KIC) Scientific travel grant to present in the World Association of Laser therapy conference held in Sao Paolo, BrazilJan 2018Global Excellence and Stature awardBursary award given for academic excellence. Also received in 2014, 2015, 2016 and 2017Oct 2014Merit Award2nd Best Oral presentation in the African Laser Student's Workshop held in MoroccoSep 2014Travel GrantTravel grant awarded for the best abstract to attend the World Association of Laser Therapy conference in USA.Jan 2014Merit AwardMasters with distinction awarded from 2014-2016Oct 2017Deans Merit award of distinctionOverall Best performing student in the laser research department, faculty of health sciences. Also awarded in 2012, 2013 and 2016Oct 2012Merit awardBest Poster presentation in the African Laser student Workshop held in Windhoek, NamibiaOct 2013Special Residential AwardOutstanding Postgraduate Work by the Student Accommodation and Residence LifeOct 2012Merit AwardGood Leadership by the Student Accommodation and Residence life. Was also awarded in 2010 and 2011Jan 2017Bursary AwardAwarded by the African Laser Centre to study Masters and PhD. Also awarded in 2012, 2013, 2014 and 2015