Full Member
Glory Enjong Mbah
Membership since:
2025
Field of activity:
Degrees:
2019
Doctorate Biological Systems and Organisms
Human Onchocerciasis is a debilitating neglected tropical disease caused by the filarial nematodeOnchocerca volvulus, and affecting 18 million people globally, with approximately 2 million from Cameroon. The only MDA recommended drug; ivermectin, has registered some limitations, including current reports of possible resistance in Cameroon. In addition to that, the recently approved moxidectin is only microfilaricidal like ivermectin hence the need for a macrofilaricidal drug, given that the adult worms can last up to 15 years in humans. Cattle harbor a very closely related variant to the nematode parasite in humans, but screening novel drugs or vaccines in animals is expensive, hence the need for rodents. Having developed and validated 4 rodents for the purpose of screening new drugs or vaccines, we are currently applying the second model to screen new vaccine candidates against onchocerciasis.
2012
Master Biological Systems and Organisms
Involved understanding the overall process of drug discovery from concept to drug, its challenges, conflicts of interest and modern aspects surrounding it. Basic principles of NMR, Mass Spec, X-ray Crystllography and HPLC. Fundamental knowledge on drug development and the dilemma of pharma companies between making profit and saving lives, pharmacovigilence, pharmamanagement, and functioning of regulatory authorities also acquired.
2010
Undergraduate Biological Systems and Organisms